SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oi8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 2oi8 PUTATIVE REGULATORY
PROTEIN SCO4313
(Streptomyces
coelicolor) 		4 / 6 LEU A  67
PHE A  57
ILE A  21
ALA A  25
 None
 1.04A 2j5mA-2oi8A:
undetectable		 2j5mA-2oi8A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 2oi8 PUTATIVE REGULATORY
PROTEIN SCO4313
(Streptomyces
coelicolor) 		5 / 8 ARG A  45
ILE A  42
ASP A  61
GLY A  59
TYR A 118
 None
 1.44A 2tsrB-2oi8A:
undetectable		 2tsrB-2oi8A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 2oi8 PUTATIVE REGULATORY
PROTEIN SCO4313
(Streptomyces
coelicolor) 		5 / 12 HIS A  94
LEU A  79
ALA A 100
LEU A 183
PHE A 179
 None
 1.09A 4qdcA-2oi8A:
undetectable		 4qdcA-2oi8A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 2oi8 PUTATIVE REGULATORY
PROTEIN SCO4313
(Streptomyces
coelicolor) 		5 / 10 ALA A 138
LEU A 214
LEU A  92
SER A  85
ALA A  82
 None
 0.98A 4zbrA-2oi8A:
3.2		 4zbrA-2oi8A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2oi8 PUTATIVE REGULATORY
PROTEIN SCO4313
(Streptomyces
coelicolor) 		6 / 12 GLY A  86
VAL A 134
THR A 131
ALA A  90
LEU A  92
ALA A  95
 None
 1.35A 5kpcA-2oi8A:
undetectable		 5kpcA-2oi8A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 2oi8 PUTATIVE REGULATORY
PROTEIN SCO4313
(Streptomyces
coelicolor) 		4 / 8 HIS A 184
PHE A 111
GLN A  75
THR A 131
 None
 1.22A 5u6nA-2oi8A:
undetectable		 5u6nA-2oi8A:
19.77