SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oiw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TJ7_A_ACTA604_0 (GBAA_1210 PROTEIN)	2oiw	PUTATIVE 4-HYDROXYBENZOYL-COA THIOESTERASE (Geobacillus stearothermophil us)	4 / 6	GLY A 79 VAL A 102 SER A 82 THR A 84	None	1.00A	3tj7A-2oiwA: undetectable 3tj7B-2oiwA: undetectable	3tj7A-2oiwA: 24.39 3tj7B-2oiwA: 24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TJ7_C_ACTC606_0 (GBAA_1210 PROTEIN)	2oiw	PUTATIVE 4-HYDROXYBENZOYL-COA THIOESTERASE (Geobacillus stearothermophil us)	4 / 6	GLY A 79 VAL A 102 SER A 82 THR A 84	None	1.02A	3tj7C-2oiwA: undetectable 3tj7D-2oiwA: undetectable	3tj7C-2oiwA: 24.39 3tj7D-2oiwA: 24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TJ7_D_ACTD605_0 (GBAA_1210 PROTEIN)	2oiw	PUTATIVE 4-HYDROXYBENZOYL-COA THIOESTERASE (Geobacillus stearothermophil us)	4 / 6	VAL A 102 SER A 82 THR A 84 GLY A 79	None	1.02A	3tj7C-2oiwA: undetectable 3tj7D-2oiwA: undetectable	3tj7C-2oiwA: 24.39 3tj7D-2oiwA: 24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FHW_A_ACRA801_2 (GLUCOAMYLASE P)	2oiw	PUTATIVE 4-HYDROXYBENZOYL-COA THIOESTERASE (Geobacillus stearothermophil us)	3 / 3	TRP A 129 GLU A 76 GLU A 87	None	0.95A	6fhwA-2oiwA: undetectable	6fhwA-2oiwA: 17.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3TJ7_A_ACTA604_0","GBAA_1210 PROTEIN","2oiw","PUTATIVE 4-HYDROXYBENZOYL-COA THIOESTERASE","Geobacillus stearothermophilus",4,"GLY A  79;VAL A 102;SER A  82;THR A  84","None","1.00A","3tj7A-2oiwA:undetectable;3tj7B-2oiwA:undetectable","3tj7A-2oiwA:24.39;3tj7B-2oiwA:24.39"],["3TJ7_C_ACTC606_0","GBAA_1210 PROTEIN","2oiw","PUTATIVE 4-HYDROXYBENZOYL-COA THIOESTERASE","Geobacillus stearothermophilus",4,"GLY A  79;VAL A 102;SER A  82;THR A  84","None","1.02A","3tj7C-2oiwA:undetectable;3tj7D-2oiwA:undetectable","3tj7C-2oiwA:24.39;3tj7D-2oiwA:24.39"],["3TJ7_D_ACTD605_0","GBAA_1210 PROTEIN","2oiw","PUTATIVE 4-HYDROXYBENZOYL-COA THIOESTERASE","Geobacillus stearothermophilus",4,"VAL A 102;SER A  82;THR A  84;GLY A  79","None","1.02A","3tj7C-2oiwA:undetectable;3tj7D-2oiwA:undetectable","3tj7C-2oiwA:24.39;3tj7D-2oiwA:24.39"],["6FHW_A_ACRA801_2","GLUCOAMYLASE P","2oiw","PUTATIVE 4-HYDROXYBENZOYL-COA THIOESTERASE","Geobacillus stearothermophilus",3,"TRP A 129;GLU A  76;GLU A  87","None","0.95A","6fhwA-2oiwA:undetectable","6fhwA-2oiwA:17.83"]]