SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oix'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 11 THR A 348
LEU A 475
VAL A 474
GLY A 477
VAL A 414
 None
 1.26A 1akdA-2oixA:
undetectable		 1akdA-2oixA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		4 / 4 ARG A 354
ALA A 352
ALA A 482
GLU A 479
 None
 1.26A 1e7bB-2oixA:
undetectable		 1e7bB-2oixA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 9 LEU A 512
GLY A 471
GLY A 477
ILE A 478
ILE A 508
 None
 1.01A 1hpvA-2oixA:
undetectable		 1hpvA-2oixA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_A_RBFA501_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 12 TRP A 410
GLY A 471
LEU A 412
ILE A 478
ILE A 508
 None
 1.26A 1kyvA-2oixA:
undetectable
1kyvE-2oixA:
undetectable		 1kyvA-2oixA:
22.06
1kyvE-2oixA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_C_RBFC503_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 12 ILE A 508
TRP A 410
GLY A 471
LEU A 412
ILE A 478
 None
 1.26A 1kyvB-2oixA:
undetectable
1kyvC-2oixA:
undetectable		 1kyvB-2oixA:
22.06
1kyvC-2oixA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_D_RBFD504_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 12 ILE A 508
TRP A 410
GLY A 471
LEU A 412
ILE A 478
 None
 1.26A 1kyvC-2oixA:
undetectable
1kyvD-2oixA:
undetectable		 1kyvC-2oixA:
22.06
1kyvD-2oixA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_E_RBFE505_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 12 ILE A 508
TRP A 410
GLY A 471
LEU A 412
ILE A 478
 None
 1.26A 1kyvD-2oixA:
undetectable
1kyvE-2oixA:
undetectable		 1kyvD-2oixA:
22.06
1kyvE-2oixA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 10 ALA A 425
LEU A 451
ALA A 446
SER A 411
LEU A 412
 None
 1.06A 2bxgB-2oixA:
undetectable		 2bxgB-2oixA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 10 THR A 348
LEU A 475
VAL A 474
GLY A 477
VAL A 414
 None
 1.27A 2cp4A-2oixA:
undetectable		 2cp4A-2oixA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		4 / 6 LEU A 413
SER A 411
ASP A 429
GLU A 458
 None
 1.18A 2j2pE-2oixA:
undetectable
2j2pF-2oixA:
undetectable		 2j2pE-2oixA:
22.75
2j2pF-2oixA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DU2_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT B7)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		4 / 7 ALA A 482
PHE A 366
ALA A 352
ALA A 361
 None
 0.94A 4du2B-2oixA:
undetectable		 4du2B-2oixA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 10 PHE A 366
GLU A 479
LEU A 512
ALA A 346
ALA A 352
 None
 1.31A 4wnuD-2oixA:
undetectable		 4wnuD-2oixA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 12 LEU A 498
PHE A 400
PHE A 366
LEU A 412
VAL A 414
 None
 1.35A 6a93B-2oixA:
undetectable		 6a93B-2oixA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN1_B_LLLB302_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE)		 2oix XANTHOMONAS OUTER
PROTEIN D
(Xanthomonas
euvesicatoria) 		5 / 10 TRP A 410
GLY A 471
ASP A 497
THR A 499
THR A 476
 None
 1.49A 6mn1B-2oixA:
0.0		 6mn1B-2oixA:
23.37