SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oj4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 2oj4 REGULATOR OF
G-PROTEIN SIGNALING
3
(Homo
sapiens) 		5 / 12 LEU A  22
GLY A  21
LEU A  12
MET A 109
LEU A  29
 None
 1.28A 1nhzA-2oj4A:
undetectable		 1nhzA-2oj4A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2oj4 REGULATOR OF
G-PROTEIN SIGNALING
3
(Homo
sapiens) 		3 / 3 LEU A  78
TRP A  41
TYR A  67
 None
 1.01A 3aicA-2oj4A:
undetectable		 3aicA-2oj4A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2oj4 REGULATOR OF
G-PROTEIN SIGNALING
3
(Homo
sapiens) 		3 / 3 LEU A  78
TRP A  41
TYR A  67
 None
 1.01A 3aicB-2oj4A:
undetectable		 3aicB-2oj4A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 2oj4 REGULATOR OF
G-PROTEIN SIGNALING
3
(Homo
sapiens) 		3 / 3 LEU A  78
TRP A  41
TYR A  67
 None
 1.01A 3aicH-2oj4A:
undetectable		 3aicH-2oj4A:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 2oj4 REGULATOR OF
G-PROTEIN SIGNALING
3
(Homo
sapiens) 		5 / 10 ILE A  68
ALA A  60
ASN A  89
LEU A  90
VAL A  93
 None
 1.16A 3o02A-2oj4A:
4.1
3o02B-2oj4A:
3.4		 3o02A-2oj4A:
21.09
3o02B-2oj4A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 2oj4 REGULATOR OF
G-PROTEIN SIGNALING
3
(Homo
sapiens) 		4 / 6 PHE A 117
GLY A  21
TYR A 123
ALA A   5
 None
 1.28A 4yshB-2oj4A:
undetectable		 4yshB-2oj4A:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 2oj4 REGULATOR OF
G-PROTEIN SIGNALING
3
(Homo
sapiens) 		5 / 12 LEU A  22
GLY A  21
SER A  11
GLU A  13
LEU A  38
 None
 1.15A 5czyA-2oj4A:
undetectable		 5czyA-2oj4A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 2oj4 REGULATOR OF
G-PROTEIN SIGNALING
3
(Homo
sapiens) 		5 / 12 LEU A  22
GLY A  21
TYR A 123
GLU A  13
LEU A  38
 None
 1.23A 5czyA-2oj4A:
undetectable		 5czyA-2oj4A:
16.40