SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ojq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		4 / 8 TYR A 677
PHE A 676
ARG A 446
LEU A 499
 None
 0.97A 1ea1A-2ojqA:
undetectable		 1ea1A-2ojqA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		4 / 7 THR A 389
LEU A 391
GLY A 394
LEU A 396
 None
 1.02A 1gtiE-2ojqA:
undetectable		 1gtiE-2ojqA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 391
LEU A 396
VAL A 395
GLN A 622
ARG A 566
 None
 1.14A 1kt4A-2ojqA:
undetectable		 1kt4A-2ojqA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		5 / 11 LEU A 391
LEU A 396
VAL A 395
GLN A 622
ARG A 566
 None
 1.15A 1kt6A-2ojqA:
undetectable		 1kt6A-2ojqA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		5 / 11 LEU A 391
LEU A 396
VAL A 395
GLN A 622
ARG A 566
 None
 1.16A 1kt7A-2ojqA:
undetectable		 1kt7A-2ojqA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		4 / 8 ASN A 655
THR A 519
LEU A 522
ALA A 533
 None
 0.98A 3kp6A-2ojqA:
1.6		 3kp6A-2ojqA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I1R_A_LZUA801_1
(MUCOSA-ASSOCIATED
LYMPHOID TISSUE
LYMPHOMA
TRANSLOCATION
PROTEIN 1)		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 503
VAL A 498
LEU A 443
LEU A 444
LEU A 684
 None
 1.14A 4i1rA-2ojqA:
undetectable		 4i1rA-2ojqA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKI_A_IMNA201_1
(TRANSTHYRETIN)		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		3 / 3 LYS A 471
LEU A 468
ALA A 470
 None
 0.74A 4ikiA-2ojqA:
undetectable		 4ikiA-2ojqA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		5 / 11 ARG A 496
LEU A 499
ASP A 452
LEU A 451
LEU A 444
 None
 1.31A 4or0A-2ojqA:
undetectable		 4or0A-2ojqA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		5 / 12 THR A 389
LEU A 391
ALA A 392
LEU A 396
LEU A 626
 None
 1.05A 4xi3C-2ojqA:
undetectable		 4xi3C-2ojqA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_1
()		 2ojq PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN
(Homo
sapiens) 		4 / 8 LEU A 401
LEU A 399
LEU A 625
GLY A 624
 None
 0.95A 6ce2A-2ojqA:
undetectable		 6ce2A-2ojqA:
15.73