SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2okf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_A_ACTA1871_0 (FPRA)	2okf	FDXN ELEMENT EXCISION CONTROLLING FACTOR PROTEIN (Trichormus variabilis)	4 / 7	PRO A 113 ALA A 68 PHE A 62 PHE A 72	None	1.19A	1lqtA-2okfA: undetectable	1lqtA-2okfA: 16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_A_ACTA1428_0 (FPRA)	2okf	FDXN ELEMENT EXCISION CONTROLLING FACTOR PROTEIN (Trichormus variabilis)	4 / 7	PRO A 113 ALA A 68 PHE A 62 PHE A 72	None	1.19A	1lquA-2okfA: undetectable	1lquA-2okfA: 16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDV_A_CL6A506_1 (CHOLESTEROL 24-HYDROXYLASE)	2okf	FDXN ELEMENT EXCISION CONTROLLING FACTOR PROTEIN (Trichormus variabilis)	5 / 9	LEU A 125 VAL A 59 GLU A 132 ALA A 14 THR A 13	None	1.06A	3mdvA-2okfA: undetectable	3mdvA-2okfA: 17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q0B_A_NVPA901_1 (HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT)	2okf	FDXN ELEMENT EXCISION CONTROLLING FACTOR PROTEIN (Trichormus variabilis)	4 / 8	LEU A 86 LYS A 88 VAL A 31 TYR A 82	None	1.15A	4q0bA-2okfA: 2.6	4q0bA-2okfA: 14.60

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LQT_A_ACTA1871_0","FPRA","2okf","FDXN ELEMENT EXCISION CONTROLLING FACTOR PROTEIN","Trichormus variabilis",4,"PRO A 113;ALA A  68;PHE A  62;PHE A  72","None","1.19A","1lqtA-2okfA:undetectable","1lqtA-2okfA:16.48"],["1LQU_A_ACTA1428_0","FPRA","2okf","FDXN ELEMENT EXCISION CONTROLLING FACTOR PROTEIN","Trichormus variabilis",4,"PRO A 113;ALA A  68;PHE A  62;PHE A  72","None","1.19A","1lquA-2okfA:undetectable","1lquA-2okfA:16.48"],["3MDV_A_CL6A506_1","CHOLESTEROL 24-HYDROXYLASE","2okf","FDXN ELEMENT EXCISION CONTROLLING FACTOR PROTEIN","Trichormus variabilis",5,"LEU A 125;VAL A  59;GLU A 132;ALA A  14;THR A  13","None","1.06A","3mdvA-2okfA:undetectable","3mdvA-2okfA:17.08"],["4Q0B_A_NVPA901_1","HIV-1 REVERSE TRANSCRIPTASE, P66 SUBUNIT","2okf","FDXN ELEMENT EXCISION CONTROLLING FACTOR PROTEIN","Trichormus variabilis",4,"LEU A  86;LYS A  88;VAL A  31;TYR A  82","None","1.15A","4q0bA-2okfA:2.6","4q0bA-2okfA:14.60"]]