SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2okj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 4 THR A 113
LEU A 117
VAL A 120
LEU A 124
 None
 0.66A 1fbmB-2okjA:
undetectable		 1fbmB-2okjA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 4 THR A 113
LEU A 117
VAL A 120
LEU A 124
 None
 0.78A 1fbmD-2okjA:
undetectable		 1fbmD-2okjA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 5 THR A 113
LEU A 117
VAL A 120
LEU A 124
 None
 0.62A 1fbmE-2okjA:
undetectable		 1fbmE-2okjA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 7 THR A 136
SER A 135
ARG A 181
TYR A 178
 None
 1.12A 1ibgL-2okjA:
undetectable		 1ibgL-2okjA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 4 THR A 113
LEU A 117
VAL A 120
LEU A 124
 None
 0.81A 1mz9D-2okjA:
undetectable		 1mz9D-2okjA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 5 GLU A 226
LEU A 230
ASP A 245
LEU A 424
 None
 1.13A 1n13B-2okjA:
undetectable
1n13C-2okjA:
undetectable		 1n13B-2okjA:
13.40
1n13C-2okjA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 4 LEU A 417
VAL A 418
ILE A 416
TRP A 401
 None
 1.38A 1s9qB-2okjA:
undetectable		 1s9qB-2okjA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 6 VAL A 337
LEU A 282
PHE A 303
MET A 276
 None
 1.12A 1x8vA-2okjA:
undetectable		 1x8vA-2okjA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 ASN A 256
PRO A 403
LEU A 417
ILE A 416
SER A 249
 LLP  A 405 ( 4.6A)
None
None
None
None
 1.31A 2xrlA-2okjA:
undetectable		 2xrlA-2okjA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		3 / 3 ASN A 212
ASP A 460
GLN A 412
 None
 0.83A 3eeyC-2okjA:
4.0		 3eeyC-2okjA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCN_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 7 MET A 261
LEU A 301
SER A 398
GLY A 252
 None
None
None
LLP  A 405 ( 3.4A)
 1.10A 3hcnA-2okjA:
4.2		 3hcnA-2okjA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		3 / 3 ARG A 186
GLU A 585
TYR A 489
 None
 0.88A 3k37B-2okjA:
undetectable		 3k37B-2okjA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 6 ILE A 254
ALA A 253
ALA A 375
THR A 400
 None
LLP  A 405 ( 3.4A)
LLP  A 405 ( 3.6A)
None
 1.03A 3mdrB-2okjA:
undetectable		 3mdrB-2okjA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 8 PHE A 324
ILE A 319
ALA A 360
VAL A 372
 None
 0.90A 3me6B-2okjA:
undetectable		 3me6B-2okjA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 8 ASP A 243
GLY A 246
ILE A 416
VAL A 237
 None
 0.79A 3nu9A-2okjA:
undetectable		 3nu9A-2okjA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 9 GLY A 378
GLY A 379
MET A 407
VAL A 409
ILE A 236
 None
 1.17A 3owxA-2okjA:
2.8		 3owxA-2okjA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.87A 3p97C-2okjA:
undetectable		 3p97C-2okjA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		3 / 3 THR A 576
SER A 578
ARG A 134
 None
 0.82A 3phnA-2okjA:
undetectable		 3phnA-2okjA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 7 LEU A 583
ALA A 575
GLY A 194
THR A 552
 None
 0.84A 3spkB-2okjA:
undetectable		 3spkB-2okjA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 7 ALA A 415
ILE A 416
ARG A 457
GLY A 246
 None
 0.97A 3v4tH-2okjA:
undetectable		 3v4tH-2okjA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 8 LEU A 200
VAL A 121
TYR A 127
LEU A 195
 None
 1.07A 3v81A-2okjA:
undetectable		 3v81A-2okjA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 ALA A 375
ASN A 402
ILE A 393
VAL A 372
HIS A 371
 LLP  A 405 ( 3.6A)
LLP  A 405 ( 3.8A)
None
None
None
 1.26A 4azsA-2okjA:
2.5		 4azsA-2okjA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.86A 4ctjC-2okjA:
undetectable		 4ctjC-2okjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.87A 4ctkC-2okjA:
undetectable		 4ctkC-2okjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 8 ARG A 186
ASN A 572
GLY A 194
ASP A 196
THR A 576
 None
 1.50A 4eyrB-2okjA:
undetectable		 4eyrB-2okjA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 8 MET A 261
SER A 398
VAL A 418
GLY A 252
 None
None
None
LLP  A 405 ( 3.4A)
 0.93A 4mk4A-2okjA:
4.6		 4mk4A-2okjA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA601_1
(SERUM ALBUMIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 11 PHE A 353
GLY A 351
THR A 511
LEU A 484
SER A 383
 None
 1.34A 4or0A-2okjA:
0.4		 4or0A-2okjA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 378
HIS A 510
SER A 398
HIS A 371
SER A 259
 None
 1.20A 4pooB-2okjA:
4.7		 4pooB-2okjA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 202
ASP A 196
PHE A 476
ILE A 198
ALA A 470
 None
 1.41A 4wh5A-2okjA:
undetectable		 4wh5A-2okjA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 11 LEU A 124
LEU A 165
LEU A 169
ILE A 168
LEU A 103
 None
 0.99A 4zowA-2okjA:
undetectable		 4zowA-2okjA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.83A 5e9qC-2okjA:
undetectable		 5e9qC-2okjA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.85A 5ec8C-2okjA:
undetectable		 5ec8C-2okjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.89A 5ehgA-2okjA:
undetectable		 5ehgA-2okjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.87A 5ehgC-2okjA:
undetectable		 5ehgC-2okjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.86A 5eifC-2okjA:
undetectable		 5eifC-2okjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.87A 5ekxB-2okjA:
undetectable		 5ekxB-2okjA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 246
ASP A 373
HIS A 371
ALA A 263
ILE A 254
 None
LLP  A 405 ( 2.7A)
None
None
None
 1.23A 5igvA-2okjA:
undetectable		 5igvA-2okjA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 244
ALA A 396
SER A 249
ILE A 247
PHE A 248
 None
 1.22A 5ih0A-2okjA:
undetectable		 5ih0A-2okjA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.93A 5ikmA-2okjA:
undetectable		 5ikmA-2okjA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		3 / 3 GLY A 555
GLN A 557
LYS A 543
 None
 0.94A 5imsB-2okjA:
5.0		 5imsB-2okjA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 6 PRO A 508
GLY A 351
PHE A 504
ARG A 316
 None
 1.19A 5jcnB-2okjA:
undetectable		 5jcnB-2okjA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.87A 5kqrA-2okjA:
undetectable		 5kqrA-2okjA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.90A 5kqsA-2okjA:
undetectable		 5kqsA-2okjA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.85A 5m5bA-2okjA:
undetectable		 5m5bA-2okjA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.88A 5njvA-2okjA:
undetectable		 5njvA-2okjA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.89A 5njvB-2okjA:
undetectable		 5njvB-2okjA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.90A 5njvC-2okjA:
undetectable		 5njvC-2okjA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 8 VAL A 513
ILE A 494
LEU A 490
ILE A 584
ILE A 587
 None
 1.45A 5numA-2okjA:
undetectable		 5numA-2okjA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.92A 5vimA-2okjA:
undetectable		 5vimA-2okjA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.90A 5vimB-2okjA:
undetectable		 5vimB-2okjA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.98A 5wz1A-2okjA:
undetectable		 5wz1A-2okjA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.95A 5wz1C-2okjA:
undetectable		 5wz1C-2okjA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.98A 5wz1D-2okjA:
undetectable		 5wz1D-2okjA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.95A 5wz1E-2okjA:
undetectable		 5wz1E-2okjA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.98A 5wz1F-2okjA:
undetectable		 5wz1F-2okjA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 351
GLY A 379
GLY A 346
TRP A 376
ILE A 480
 None
 0.94A 5wz2C-2okjA:
undetectable		 5wz2C-2okjA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		4 / 5 HIS A 404
ALA A 375
SER A 414
GLY A 251
 LLP  A 405 ( 4.2A)
LLP  A 405 ( 3.6A)
None
LLP  A 405 ( 3.3A)
 1.22A 5yodD-2okjA:
undetectable		 5yodD-2okjA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWT_D_BEZD202_0
(PR 10 PROTEIN)		 2okj GLUTAMATE
DECARBOXYLASE 1
(Homo
sapiens) 		3 / 3 PHE A 324
ASP A 323
LYS A 327
 None
 0.87A 6awtD-2okjA:
undetectable		 6awtD-2okjA:
16.02