SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2okq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_A_DVAA6_0
(GRAMICIDIN A)		 2okq HYPOTHETICAL PROTEIN
YBAA
(Shigella
flexneri) 		3 / 3 ALA A  10
VAL A  67
TRP A  42
 None
 0.88A 1magA-2okqA:
undetectable		 1magA-2okqA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAG_B_DVAB6_0
(GRAMICIDIN A)		 2okq HYPOTHETICAL PROTEIN
YBAA
(Shigella
flexneri) 		3 / 3 ALA A  10
VAL A  67
TRP A  42
 None
 0.88A 1magB-2okqA:
undetectable		 1magB-2okqA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 2okq HYPOTHETICAL PROTEIN
YBAA
(Shigella
flexneri) 		3 / 3 ALA A  10
VAL A  67
TRP A  42
 None
 0.74A 1nt6A-2okqA:
undetectable		 1nt6A-2okqA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 2okq HYPOTHETICAL PROTEIN
YBAA
(Shigella
flexneri) 		3 / 3 ALA A  10
VAL A  67
TRP A  42
 None
 0.74A 1nt6B-2okqA:
undetectable		 1nt6B-2okqA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2okq HYPOTHETICAL PROTEIN
YBAA
(Shigella
flexneri) 		4 / 7 PHE A 111
ARG A  79
ASP A   5
TYR A 108
 None
 1.19A 2e5dA-2okqA:
undetectable
2e5dB-2okqA:
undetectable		 2e5dA-2okqA:
14.17
2e5dB-2okqA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2okq HYPOTHETICAL PROTEIN
YBAA
(Shigella
flexneri) 		4 / 7 ASP A   5
TYR A 108
PHE A 111
ARG A  79
 None
 1.19A 2e5dA-2okqA:
undetectable
2e5dB-2okqA:
undetectable		 2e5dA-2okqA:
14.17
2e5dB-2okqA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2okq HYPOTHETICAL PROTEIN
YBAA
(Shigella
flexneri) 		5 / 12 ALA A  82
LYS A  85
MET A  92
ALA A  26
ILE A  38
 None
 0.99A 3ut5B-2okqA:
undetectable		 3ut5B-2okqA:
15.97