SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2okv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 2okv PROBABLE
D-TYROSYL-TRNA(TYR)
DEACYLASE 1
(Homo
sapiens) 		4 / 6 LEU A  75
ILE A 135
VAL A   8
ALA A  11
 None
 0.78A 2j5mA-2okvA:
undetectable		 2j5mA-2okvA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2okv PROBABLE
D-TYROSYL-TRNA(TYR)
DEACYLASE 1
(Homo
sapiens) 		4 / 7 GLN A  19
ILE A 135
SER A  21
CYH A  28
 None
None
None
MG  A1201 (-4.1A)
 1.42A 2xz5D-2okvA:
undetectable
2xz5E-2okvA:
undetectable		 2xz5D-2okvA:
19.56
2xz5E-2okvA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XMF_A_HSMA202_1
(NITROPHORIN-7)		 2okv PROBABLE
D-TYROSYL-TRNA(TYR)
DEACYLASE 1
(Homo
sapiens) 		3 / 3 ASP A  37
LEU A  31
GLY A  32
 None
 0.57A 4xmfA-2okvA:
undetectable		 4xmfA-2okvA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 2okv PROBABLE
D-TYROSYL-TRNA(TYR)
DEACYLASE 1
(Homo
sapiens) 		4 / 4 VAL A   5
ILE A  74
ASN A  51
VAL A  46
 MG  A1201 ( 4.9A)
None
None
None
 1.14A 5ajqA-2okvA:
undetectable		 5ajqA-2okvA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_B_FUAB1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2okv PROBABLE
D-TYROSYL-TRNA(TYR)
DEACYLASE 1
(Homo
sapiens) 		4 / 5 ILE A  33
LEU A 145
LYS A  48
HIS A  44
 None
 1.00A 5jmnB-2okvA:
undetectable		 5jmnB-2okvA:
11.45