SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2okx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 8 TRP A 383
GLY A 244
TYR A 245
TRP A 272
 None
 1.05A 1maaD-2okxA:
undetectable		 1maaD-2okxA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 5 ASP A 162
LEU A 159
ALA A 164
LEU A 165
 None
 1.10A 1nh8A-2okxA:
undetectable		 1nh8A-2okxA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 THR A 188
THR A 184
PRO A 186
 None
 0.86A 1qfiB-2okxA:
undetectable		 1qfiB-2okxA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 10 ASP A 683
ASP A 750
SER A 763
TRP A 684
TYR A 843
 None
None
None
None
GOL  A3019 (-4.0A)
 1.49A 1rqpB-2okxA:
0.5		 1rqpB-2okxA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_2
(DIPEPTIDYL PEPTIDASE
IV)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 ARG A 447
SER A 496
TYR A 497
 GOL  A3035 (-3.0A)
None
GOL  A3002 (-4.7A)
 0.70A 1x70A-2okxA:
undetectable		 1x70A-2okxA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 THR A 184
PRO A 186
THR A 188
 None
 0.75A 209dC-2okxA:
undetectable		 209dC-2okxA:
2.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 6 TRP A 900
PHE A 539
SER A 538
ARG A 540
 GOL  A3006 (-4.3A)
None
None
None
 1.29A 2a3cB-2okxA:
undetectable		 2a3cB-2okxA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 SER A 800
ASP A 579
CYH A 560
 None
GOL  A3007 (-2.6A)
None
 1.15A 2br4E-2okxA:
undetectable		 2br4E-2okxA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_A_TPFA2472_1
(CYTOCHROME P450 121)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 11 THR A 660
VAL A 657
ALA A 636
SER A 580
PHE A 575
 None
 1.23A 2ij7A-2okxA:
0.0		 2ij7A-2okxA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_D_TPFD2473_1
(CYTOCHROME P450 121)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 10 THR A 660
VAL A 657
ALA A 636
SER A 580
PHE A 575
 None
 1.24A 2ij7D-2okxA:
undetectable		 2ij7D-2okxA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 PHE A 505
LEU A 443
ARG A 554
ARG A 502
 None
 0.91A 2jn3A-2okxA:
undetectable		 2jn3A-2okxA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 6 LEU A  52
VAL A  54
ILE A  90
ILE A  44
 None
 0.87A 2piwA-2okxA:
undetectable		 2piwA-2okxA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 ILE A 687
ILE A 752
LEU A 740
ILE A 749
 None
 0.83A 2q83A-2okxA:
undetectable		 2q83A-2okxA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 LEU A 429
PRO A 430
ARG A 513
 None
 0.56A 2qd4B-2okxA:
undetectable		 2qd4B-2okxA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 SER A 241
THR A 342
PHE A 387
 None
 0.66A 2x91A-2okxA:
undetectable		 2x91A-2okxA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 12 ILE A  78
PHE A  30
ALA A 176
LEU A 111
ILE A  90
 None
 1.03A 2xkwB-2okxA:
undetectable		 2xkwB-2okxA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 SER A 448
ARG A 447
GLN A 528
 None
GOL  A3035 (-3.0A)
GOL  A3023 ( 4.6A)
 0.88A 2xnrA-2okxA:
undetectable		 2xnrA-2okxA:
7.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_1
(ADENOSYLHOMOCYSTEINA
SE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 12 THR A 530
GLU A 535
LEU A 203
HIS A 555
PHE A 591
 None
None
None
GOL  A3035 (-3.7A)
None
 1.33A 2zj0C-2okxA:
undetectable		 2zj0C-2okxA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 8 ILE A 195
SER A 529
ARG A 502
ASP A  74
 None
 1.10A 2zw9B-2okxA:
undetectable		 2zw9B-2okxA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 12 ARG A 487
PHE A 486
GLY A 151
ILE A 154
PHE A 453
 None
 1.13A 2zzmA-2okxA:
undetectable		 2zzmA-2okxA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_B_VD3B2001_1
(VITAMIN D
HYDROXYLASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 11 ILE A 653
LEU A 661
LEU A 712
ILE A 634
PRO A 605
 None
 1.25A 3a50B-2okxA:
undetectable		 3a50B-2okxA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1100_1
(SERUM ALBUMIN)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 4 LEU A 111
ARG A   4
LEU A  42
ALA A   8
 None
 1.18A 3b9mA-2okxA:
undetectable		 3b9mA-2okxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 6 HIS A 299
GLN A 278
LEU A 294
LEU A 292
 None
 0.95A 3bgdA-2okxA:
undetectable		 3bgdA-2okxA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 HIS A 299
GLN A 278
LEU A 294
LEU A 292
 None
 0.86A 3bgdB-2okxA:
undetectable		 3bgdB-2okxA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 GLY A 107
ASP A  47
SER A  48
 None
 0.72A 3brfA-2okxA:
undetectable		 3brfA-2okxA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 12 HIS A 299
VAL A 301
PHE A 316
VAL A 273
VAL A 258
 None
None
GOL  A3003 (-4.7A)
None
None
 1.24A 3czvA-2okxA:
undetectable
3czvB-2okxA:
undetectable		 3czvA-2okxA:
14.81
3czvB-2okxA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 GLU A 692
SER A 759
VAL A 761
 None
 0.78A 3eeoA-2okxA:
undetectable		 3eeoA-2okxA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 MET A 820
MET A 764
PHE A 805
 None
GOL  A3008 (-4.8A)
None
 1.26A 3gn8A-2okxA:
undetectable		 3gn8A-2okxA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 LEU A  52
TYR A  50
ILE A  11
ARG A 106
 None
 1.27A 3ik3A-2okxA:
undetectable		 3ik3A-2okxA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 LEU A  52
TYR A  50
ILE A  11
ARG A 106
 None
 1.27A 3ik3B-2okxA:
undetectable		 3ik3B-2okxA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 4 GLY A  60
TYR A  50
GLY A  62
ASP A  74
 GOL  A3001 (-3.3A)
None
None
None
 1.34A 3kl3A-2okxA:
undetectable		 3kl3A-2okxA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 11 GLU A 446
SER A 859
THR A 857
GLU A 841
HIS A 860
 None
None
None
GOL  A3007 (-4.4A)
None
 1.48A 3r76B-2okxA:
undetectable		 3r76B-2okxA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 12 GLN A 777
GLY A 774
LEU A 731
ALA A 726
ALA A 727
 None
 1.04A 3sufA-2okxA:
undetectable		 3sufA-2okxA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 6 LEU A 585
ALA A 641
THR A 644
LEU A 601
 None
 1.00A 3t3zB-2okxA:
undetectable		 3t3zB-2okxA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 5 HIS A 862
SER A 859
THR A 857
GLU A 572
 GOL  A3007 (-4.1A)
None
None
GOL  A3026 ( 2.9A)
 1.26A 3tm4A-2okxA:
undetectable		 3tm4A-2okxA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 5 HIS A 862
SER A 859
THR A 857
GLU A 572
 GOL  A3007 (-4.1A)
None
None
GOL  A3026 ( 2.9A)
 1.26A 3tm4B-2okxA:
undetectable		 3tm4B-2okxA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 TYR A  50
VAL A  92
ILE A  44
TYR A 104
 None
 0.90A 3tneB-2okxA:
undetectable		 3tneB-2okxA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 ARG A 581
ARG A 638
LYS A 704
 None
 1.33A 3w1wA-2okxA:
0.0
3w1wB-2okxA:
0.0		 3w1wA-2okxA:
16.81
3w1wB-2okxA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 8 TYR A 364
TYR A 245
LEU A 225
MET A 229
 GOL  A3017 (-4.5A)
None
None
None
 1.15A 3wipG-2okxA:
undetectable
3wipH-2okxA:
undetectable		 3wipG-2okxA:
13.44
3wipH-2okxA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 12 PRO A 868
LEU A 872
LEU A 546
LEU A 545
ILE A 824
 None
 1.12A 4a7aB-2okxA:
undetectable		 4a7aB-2okxA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 PHE A 806
ILE A 626
ASN A 628
GLU A 809
 None
 1.09A 4a97E-2okxA:
3.8		 4a97E-2okxA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 8 PHE A 806
ILE A 626
ASN A 628
GLU A 809
 None
 1.10A 4a97C-2okxA:
3.7		 4a97C-2okxA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 TYR A 470
MET A 471
ILE A 441
 None
 0.62A 4c8bB-2okxA:
undetectable		 4c8bB-2okxA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_B_ECNB403_1
(FLAVOHEMOGLOBIN)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 11 ALA A 379
LEU A 377
VAL A 384
LEU A 302
TYR A 245
 None
 1.09A 4g1bB-2okxA:
undetectable		 4g1bB-2okxA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 ILE A 784
VAL A 769
TYR A 748
ALA A 747
 None
 0.75A 4g77A-2okxA:
undetectable		 4g77A-2okxA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 6 TRP A 684
ILE A 687
THR A 766
ASP A 616
 None
 1.13A 4iaqA-2okxA:
2.6		 4iaqA-2okxA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 TRP A 684
ILE A 687
THR A 766
ASP A 616
 None
 1.12A 4iarA-2okxA:
2.7		 4iarA-2okxA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 ARG A 581
GLU A 809
ASN A 582
 None
 0.91A 4ip7D-2okxA:
undetectable		 4ip7D-2okxA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA3_L_ACTL301_0
(C2095 HEAVY CHAIN
C2095 LIGHT CHAIN)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 PRO A 627
ASN A 628
HIS A 697
 None
 0.97A 4ma3H-2okxA:
2.9
4ma3L-2okxA:
2.1		 4ma3H-2okxA:
12.82
4ma3L-2okxA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 10 LEU A 661
LEU A 702
LEU A 732
ILE A 634
THR A 696
 None
 1.39A 4mk4A-2okxA:
undetectable		 4mk4A-2okxA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 PHE A 343
ASP A 344
THR A 306
ASP A 304
 None
 1.01A 4pcuA-2okxA:
undetectable		 4pcuA-2okxA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 6 GLU A 583
THR A 557
THR A 594
HIS A 643
 None
 1.36A 4pfjB-2okxA:
undetectable		 4pfjB-2okxA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 6 ASN A 680
TYR A 664
LEU A 674
PHE A 631
 None
 1.23A 4twdB-2okxA:
3.8
4twdC-2okxA:
3.8		 4twdB-2okxA:
16.37
4twdC-2okxA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 6 ASN A 680
TYR A 664
LEU A 674
PHE A 631
 None
 1.27A 4twdD-2okxA:
3.7
4twdE-2okxA:
3.7		 4twdD-2okxA:
16.37
4twdE-2okxA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 12 VAL A 905
ILE A 935
VAL A 937
VAL A 939
LEU A 927
 None
 1.23A 4y0pA-2okxA:
undetectable		 4y0pA-2okxA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 8 ASN A 628
PRO A 627
PHE A 632
TRP A 629
 None
None
None
GOL  A3007 (-3.9A)
 1.44A 5amkA-2okxA:
undetectable		 5amkA-2okxA:
8.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CVT_B_ACTB200_0
(N5-CARBOXYAMINOIMIDA
ZOLE RIBONUCLEOTIDE
MUTASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 ASN A 646
ALA A 648
ARG A 652
 None
 0.25A 5cvtB-2okxA:
undetectable		 5cvtB-2okxA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 10 ILE A 318
LEU A 260
ILE A 249
LEU A 300
PRO A 368
 None
None
None
None
GOL  A3017 (-4.2A)
 1.09A 5ienB-2okxA:
undetectable		 5ienB-2okxA:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 ASP A 683
ASN A 849
PHE A 805
 None
 0.92A 5jglB-2okxA:
undetectable		 5jglB-2okxA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 12 PRO A 430
LEU A 211
GLU A 433
PHE A 432
GLY A 435
 None
 1.32A 5k7uA-2okxA:
undetectable		 5k7uA-2okxA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 7 TYR A 466
GLN A 209
ASP A 442
TYR A 571
 None
 1.18A 5ov9B-2okxA:
undetectable		 5ov9B-2okxA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 12 ALA A 221
PHE A 262
VAL A 258
GLN A 278
VAL A 266
 None
GOL  A3003 (-4.9A)
None
None
GOL  A3003 (-3.7A)
 0.99A 5tudD-2okxA:
undetectable		 5tudD-2okxA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 6 LEU A 337
VAL A 246
LEU A 225
VAL A 303
 None
 0.88A 5x7zA-2okxA:
undetectable		 5x7zA-2okxA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		4 / 8 PRO A 605
CYH A 637
TYR A 640
ILE A 653
 None
 0.69A 5y1yA-2okxA:
undetectable		 5y1yA-2okxA:
7.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		3 / 3 ARG A 130
ARG A  27
ASP A 170
 None
 0.94A 6d8pA-2okxA:
undetectable		 6d8pA-2okxA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 2okx RHAMNOSIDASE B
(Bacillus
sp.
GL1) 		5 / 11 VAL A 512
THR A 461
VAL A 440
LEU A 439
ALA A 457
 None
 1.20A 6dryA-2okxA:
1.2		 6dryA-2okxA:
17.50