SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ol3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		5 / 11 VAL H  34
TYR H   7
TYR H 171
GLY H 175
LEU H 179
 None
 1.40A 1i9jH-2ol3H:
12.2
1i9jL-2ol3H:
12.6		 1i9jH-2ol3H:
22.81
1i9jL-2ol3H:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 TYR H  85
TYR H 118
ILE H  95
GLY H  83
 None
 1.22A 1kifA-2ol3H:
undetectable		 1kifA-2ol3H:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 TYR H  85
TYR H 118
ILE H  95
GLY H  83
 None
 1.22A 1kifB-2ol3H:
undetectable		 1kifB-2ol3H:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 TYR H  85
TYR H 118
ILE H  95
GLY H  83
 None
 1.22A 1kifC-2ol3H:
undetectable		 1kifC-2ol3H:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 TYR H  85
TYR H 118
ILE H  95
GLY H  83
 None
 1.22A 1kifD-2ol3H:
undetectable		 1kifD-2ol3H:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 TYR H  85
TYR H 118
ILE H  95
GLY H  83
 None
 1.22A 1kifE-2ol3H:
undetectable		 1kifE-2ol3H:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 TYR H  85
TYR H 118
ILE H  95
GLY H  83
 None
 1.22A 1kifF-2ol3H:
undetectable		 1kifF-2ol3H:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 TYR H  85
TYR H 118
ILE H  95
GLY H  83
 None
 1.22A 1kifG-2ol3H:
undetectable		 1kifG-2ol3H:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 TYR H  85
TYR H 118
ILE H  95
GLY H  83
 None
 1.22A 1kifH-2ol3H:
undetectable		 1kifH-2ol3H:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 2ol3 BM3.3 T-CELL
RECEPTOR ALPHA-CHAIN
(Mus
musculus) 		5 / 9 TYR A  88
THR A  38
LEU A  46
VAL A  44
ASP A  84
 None
 1.46A 1t86B-2ol3A:
undetectable		 1t86B-2ol3A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 TYR H  85
TYR H 118
ILE H  95
GLY H  83
 None
 1.20A 1ve9A-2ol3H:
undetectable		 1ve9A-2ol3H:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		3 / 3 TRP H 167
GLU H  63
TYR H  59
 None
 0.81A 2a3aA-2ol3H:
undetectable		 2a3aA-2ol3H:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 TYR H  85
TYR H 118
ILE H  95
GLY H  83
 None
 1.15A 2du8J-2ol3H:
undetectable		 2du8J-2ol3H:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 8 TYR H 123
TYR H  84
TYR H 118
HIS H  93
 None
 0.92A 2zm8A-2ol3H:
undetectable		 2zm8A-2ol3H:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 8 TYR H 123
TYR H  84
TYR H 118
HIS H  93
 None
 0.97A 2zmaA-2ol3H:
undetectable		 2zmaA-2ol3H:
22.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_A_1KXA277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		5 / 10 ILE H  95
VAL H  97
TYR H 123
ILE H 124
TRP H 147
 None
 0.31A 3uprA-2ol3H:
30.8		 3uprA-2ol3H:
71.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UPR_C_1KXC277_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		5 / 10 ILE H  95
VAL H  97
TYR H 123
ILE H 124
TRP H 147
 None
 0.29A 3uprC-2ol3H:
31.0		 3uprC-2ol3H:
71.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VRJ_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		5 / 12 ILE H  95
VAL H  97
TYR H 123
ILE H 124
TRP H 147
 None
 0.27A 3vrjA-2ol3H:
31.0
3vrjC-2ol3H:
undetectable		 3vrjA-2ol3H:
71.01
3vrjC-2ol3H:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 8 LEU H 156
LYS H  66
TYR H   7
TRP H 167
 None
 1.21A 5hbsA-2ol3H:
undetectable		 5hbsA-2ol3H:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_2
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 5 CYH H 101
CYH H 164
LEU H   5
ASP H  29
 None
 1.30A 5mafA-2ol3H:
undetectable		 5mafA-2ol3H:
14.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		5 / 10 ILE H  95
VAL H  97
TYR H 123
ILE H 124
TRP H 147
 None
 0.25A 5u98A-2ol3H:
30.9		 5u98A-2ol3H:
71.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5U98_D_1KXD301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		5 / 10 ILE H  95
VAL H  97
TYR H 123
ILE H 124
TRP H 147
 None
 0.26A 5u98D-2ol3H:
30.9		 5u98D-2ol3H:
71.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 2ol3 ALLOGENEIC H-2KBM8
MHC CLASS I MOLECULE
(Mus
musculus) 		4 / 9 LEU H 230
VAL H 247
SER H 246
ASP H 227
 None
 0.98A 6c2mD-2ol3H:
undetectable		 6c2mD-2ol3H:
15.75