SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ol5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_A_DESA129_1
(TRANSTHYRETIN)		 2ol5 PAI 2 PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 4 LYS A 199
LEU A 196
LEU A 166
SER A 167
 None
 1.41A 1tt6A-2ol5A:
undetectable		 1tt6A-2ol5A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 2ol5 PAI 2 PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 HIS A  54
VAL A  70
LEU A  27
 None
 0.74A 4m2vA-2ol5A:
undetectable		 4m2vA-2ol5A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2ol5 PAI 2 PROTEIN
(Geobacillus
stearothermophil
us) 		3 / 3 ASN A 110
PHE A 153
TYR A  52
 None
 0.61A 4u15A-2ol5A:
undetectable		 4u15A-2ol5A:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 2ol5 PAI 2 PROTEIN
(Geobacillus
stearothermophil
us) 		4 / 6 VAL A  92
TYR A  86
ARG A 174
HIS A 170
 None
 1.31A 5kkzA-2ol5A:
undetectable
5kkzG-2ol5A:
undetectable		 5kkzA-2ol5A:
17.26
5kkzG-2ol5A:
21.40