SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ol8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		6 / 11 THR O 170
THR O 174
THR O 175
SER O 153
GLY O 154
ALA O 156
 None
 1.46A 2f162-2ol8O:
undetectable		 2f162-2ol8O:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		5 / 11 THR O 170
THR O 174
THR O 175
SER O 153
GLY O 154
 None
 1.20A 2f16N-2ol8O:
undetectable		 2f16N-2ol8O:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 8 SER O  37
SER O 120
THR O 136
THR O  97
 None
 0.92A 2v0zO-2ol8O:
undetectable		 2v0zO-2ol8O:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 7 THR O  98
GLU O 100
THR O  89
VAL O  75
 None
 0.64A 3em0B-2ol8O:
3.4		 3em0B-2ol8O:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 8 ILE O 241
PHE O 235
GLU O 180
LEU O 263
 None
 0.87A 3ua5A-2ol8O:
undetectable		 3ua5A-2ol8O:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		5 / 12 THR O 174
THR O 175
SER O 153
GLY O 154
ALA O 156
 None
 1.22A 5lf3b-2ol8O:
undetectable		 5lf3b-2ol8O:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		5 / 12 THR O 174
THR O 175
SER O 153
GLY O 154
ALA O 156
 None
 1.22A 5lf3N-2ol8O:
undetectable		 5lf3N-2ol8O:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		6 / 12 THR O 170
THR O 174
THR O 175
SER O 153
GLY O 154
ALA O 156
 None
 1.42A 5lf7V-2ol8O:
3.0
5lf7b-2ol8O:
undetectable		 5lf7V-2ol8O:
22.81
5lf7b-2ol8O:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		6 / 12 THR O 170
THR O 174
THR O 175
SER O 153
GLY O 154
ALA O 156
 None
 1.43A 5lf7H-2ol8O:
undetectable
5lf7N-2ol8O:
undetectable		 5lf7H-2ol8O:
22.81
5lf7N-2ol8O:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 8 VAL O  32
GLY O  74
LEU O  76
THR O  89
 None
 1.00A 5sxqA-2ol8O:
undetectable		 5sxqA-2ol8O:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 8 VAL O  32
GLY O  74
LEU O  76
THR O  89
 None
 1.05A 5sxqB-2ol8O:
undetectable		 5sxqB-2ol8O:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 2ol8 OUTER SURFACE
PROTEIN A
(Borreliella
burgdorferi) 		4 / 8 VAL O  32
GLY O  74
LEU O  76
THR O  89
 None
 1.01A 5syjA-2ol8O:
undetectable		 5syjA-2ol8O:
16.16