SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2olg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		4 / 8 HIS A 155
SER A 315
VAL A 334
GLY A 347
 None
 0.34A 1aq7A-2olgA:
26.4		 1aq7A-2olgA:
31.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 12 ILE A 224
LEU A 223
GLY A 142
SER A 143
LEU A 330
 None
 1.00A 2a58A-2olgA:
undetectable
2a58B-2olgA:
undetectable		 2a58A-2olgA:
20.71
2a58B-2olgA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 12 ILE A 224
LEU A 223
GLY A 142
SER A 143
LEU A 330
 None
 1.00A 2a58B-2olgA:
undetectable
2a58C-2olgA:
undetectable		 2a58B-2olgA:
20.71
2a58C-2olgA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 12 ILE A 224
LEU A 223
GLY A 142
SER A 143
LEU A 330
 None
 0.99A 2a58D-2olgA:
undetectable
2a58E-2olgA:
undetectable		 2a58D-2olgA:
20.71
2a58E-2olgA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 12 GLY A 142
ALA A 125
ILE A 236
ILE A 145
VAL A 171
 None
 0.85A 2b7zB-2olgA:
undetectable		 2b7zB-2olgA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 12 LEU A 162
ILE A 201
ALA A 167
TYR A 129
THR A 204
 None
 1.26A 2japA-2olgA:
undetectable		 2japA-2olgA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 12 LEU A 162
ILE A 201
ALA A 167
TYR A 129
THR A 204
 None
 1.25A 2japC-2olgA:
undetectable		 2japC-2olgA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 10 TYR A 210
HIS A 207
ALA A 154
ALA A 222
TYR A 355
 None
 1.41A 2r2vC-2olgA:
undetectable
2r2vF-2olgA:
undetectable
2r2vG-2olgA:
undetectable		 2r2vC-2olgA:
11.86
2r2vF-2olgA:
11.86
2r2vG-2olgA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 10 THR A 124
SER A 143
VAL A 334
GLY A 258
GLY A 313
 None
 1.22A 3ixlA-2olgA:
undetectable		 3ixlA-2olgA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		4 / 8 GLY A 361
TYR A 149
GLU A  95
ARG A 225
 None
 0.87A 3s3mA-2olgA:
undetectable		 3s3mA-2olgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 11 LEU A 320
THR A 255
VAL A 257
VAL A 117
THR A 116
 None
 1.20A 3tbgA-2olgA:
undetectable		 3tbgA-2olgA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 10 LEU A 320
THR A 255
VAL A 257
VAL A 117
THR A 116
 None
 1.17A 3tbgC-2olgA:
undetectable		 3tbgC-2olgA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CLT_A_ACRA1000_1
(1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 10 ASN A 245
GLU A 246
GLY A 332
GLU A 331
ARG A 323
 None
 1.10A 5cltA-2olgA:
0.0		 5cltA-2olgA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CLT_B_ACRB1000_1
(1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 10 ASN A 245
GLU A 246
GLY A 332
GLU A 331
ARG A 323
 None
 1.12A 5cltB-2olgA:
0.0		 5cltB-2olgA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CLT_C_ACRC1000_1
(1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 10 ASN A 245
GLU A 246
GLY A 332
GLU A 331
ARG A 323
 None
 1.18A 5cltC-2olgA:
0.0		 5cltC-2olgA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		4 / 5 VAL A 295
VAL A 293
GLY A 292
PHE A 288
 None
 1.03A 5d4nA-2olgA:
undetectable
5d4nC-2olgA:
undetectable		 5d4nA-2olgA:
16.91
5d4nC-2olgA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		4 / 7 ILE A 236
GLY A 174
LEU A 168
ASP A 198
 None
 0.72A 5hieB-2olgA:
undetectable		 5hieB-2olgA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 12 SER A 143
GLY A 317
GLY A 332
VAL A 352
THR A 350
 None
 1.29A 5o4yD-2olgA:
undetectable
5o4yE-2olgA:
undetectable		 5o4yD-2olgA:
3.90
5o4yE-2olgA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		6 / 7 GLY A 260
GLY A 313
GLY A 317
PRO A 318
GLY A 142
GLY A 141
 None
 1.20A 6ag0A-2olgA:
undetectable		 6ag0A-2olgA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 2olg PRO-PHENOLOXIDASE
ACTIVATING ENZYME-I
(Holotrichia
diomphalia) 		5 / 12 VAL A 157
PRO A  98
VAL A 230
PHE A 232
ILE A 236
 None
 1.23A 6becA-2olgA:
undetectable
6becB-2olgA:
undetectable
6becC-2olgA:
undetectable		 6becA-2olgA:
18.52
6becB-2olgA:
18.52
6becC-2olgA:
18.52