SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2om5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 2om5 CONTACTIN 2
(Homo
sapiens) 		3 / 3 ALA A 165
VAL A 121
TRP A 119
 None
 0.89A 1gmkA-2om5A:
undetectable
1gmkB-2om5A:
undetectable		 1gmkA-2om5A:
5.45
1gmkB-2om5A:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2om5 CONTACTIN 2
(Homo
sapiens) 		4 / 8 LEU A 300
ALA A 367
ILE A 374
GLY A 322
 None
 0.85A 1sv9A-2om5A:
undetectable		 1sv9A-2om5A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 2om5 CONTACTIN 2
(Homo
sapiens) 		4 / 7 ASP A 270
GLN A 225
PRO A 264
GLN A 262
 None
 1.09A 3l2vA-2om5A:
undetectable		 3l2vA-2om5A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 2om5 CONTACTIN 2
(Homo
sapiens) 		4 / 8 ASP A 270
GLN A 225
PRO A 264
GLN A 262
 None
 1.14A 3oyaA-2om5A:
undetectable		 3oyaA-2om5A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 2om5 CONTACTIN 2
(Homo
sapiens) 		4 / 6 ALA A 381
GLY A   6
PRO A   7
VAL A  87
 None
 0.92A 4dubB-2om5A:
undetectable		 4dubB-2om5A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 2om5 CONTACTIN 2
(Homo
sapiens) 		3 / 3 GLY A 133
LEU A 134
HIS A 130
 None
 0.70A 5u63A-2om5A:
undetectable		 5u63A-2om5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 2om5 CONTACTIN 2
(Homo
sapiens) 		3 / 3 GLY A 133
LEU A 134
HIS A 130
 None
 0.67A 5u63B-2om5A:
undetectable		 5u63B-2om5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 2om5 CONTACTIN 2
(Homo
sapiens) 		4 / 8 VAL A 238
PHE A 232
THR A 167
GLY A 151
 None
 1.02A 5v0vA-2om5A:
undetectable		 5v0vA-2om5A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 2om5 CONTACTIN 2
(Homo
sapiens) 		3 / 3 LYS A  44
LEU A  82
ARG A  42
 None
 0.91A 5yw0A-2om5A:
undetectable		 5yw0A-2om5A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 2om5 CONTACTIN 2
(Homo
sapiens) 		3 / 3 LEU A 355
SER A 353
PHE A 352
 None
 0.56A 6fgcA-2om5A:
undetectable		 6fgcA-2om5A:
23.21