SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2omd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2omd MOLYBDOPTERIN-CONVER
TING FACTOR SUBUNIT
2
(Aquifex
aeolicus) 		4 / 6 ARG A  20
GLY A  17
ALA A  18
HIS A  86
 None
NA  A 701 (-3.6A)
NA  A 701 (-3.9A)
None
 0.99A 1wmqA-2omdA:
undetectable		 1wmqA-2omdA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2omd MOLYBDOPTERIN-CONVER
TING FACTOR SUBUNIT
2
(Aquifex
aeolicus) 		4 / 6 ARG A  20
GLY A  17
ALA A  18
HIS A  86
 None
NA  A 701 (-3.6A)
NA  A 701 (-3.9A)
None
 0.99A 1wmqB-2omdA:
undetectable		 1wmqB-2omdA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2omd MOLYBDOPTERIN-CONVER
TING FACTOR SUBUNIT
2
(Aquifex
aeolicus) 		4 / 6 ARG A  20
GLY A  17
ALA A  18
HIS A  86
 None
NA  A 701 (-3.6A)
NA  A 701 (-3.9A)
None
 0.97A 1wpuA-2omdA:
undetectable		 1wpuA-2omdA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 2omd MOLYBDOPTERIN-CONVER
TING FACTOR SUBUNIT
2
(Aquifex
aeolicus) 		4 / 6 ARG A  20
GLY A  17
ALA A  18
HIS A  86
 None
NA  A 701 (-3.6A)
NA  A 701 (-3.9A)
None
 0.98A 1wpuB-2omdA:
undetectable		 1wpuB-2omdA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_0
(UNCHARACTERIZED
PROTEIN)		 2omd MOLYBDOPTERIN-CONVER
TING FACTOR SUBUNIT
2
(Aquifex
aeolicus) 		5 / 12 LEU A  36
CYH A 115
VAL A 119
LEU A  38
ILE A  40
 None
None
None
NA  A 701 ( 4.9A)
None
 1.15A 3ijdB-2omdA:
undetectable		 3ijdB-2omdA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 2omd MOLYBDOPTERIN-CONVER
TING FACTOR SUBUNIT
2
(Aquifex
aeolicus) 		4 / 6 ALA A  63
ILE A 128
LEU A  11
GLU A  66
 None
 0.89A 3r9sA-2omdA:
undetectable		 3r9sA-2omdA:
21.51