SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2omv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_2
(LIVER
CARBOXYLESTERASE I)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		3 / 3 PHE A 193
LEU A 203
LEU A 209
 None
 0.62A 1mx1E-2omvA:
undetectable		 1mx1E-2omvA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 11 ASN A 261
GLY A 260
VAL A 219
ILE A 235
ILE A 241
 None
 0.90A 1n49B-2omvA:
undetectable		 1n49B-2omvA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 11 ASN A 261
GLY A 260
VAL A 219
ILE A 235
ILE A 241
 None
 0.92A 1n49C-2omvA:
undetectable		 1n49C-2omvA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 6 PHE A 368
ASN A 371
ASN A 393
GLY A 391
 None
 1.10A 1oniD-2omvA:
undetectable
1oniF-2omvA:
undetectable		 1oniD-2omvA:
15.47
1oniF-2omvA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 6 LEU A 324
ARG A 365
THR A 342
LEU A 341
 None
 1.06A 1v54A-2omvA:
undetectable
1v54J-2omvA:
undetectable		 1v54A-2omvA:
22.56
1v54J-2omvA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 9 GLY A 391
ALA A 390
LEU A 412
PHE A 368
LEU A 401
 None
 1.12A 1y7iA-2omvA:
undetectable		 1y7iA-2omvA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 11 ILE A 103
ILE A 125
GLY A  93
LEU A 110
PHE A 105
 None
 1.21A 2azyA-2omvA:
undetectable		 2azyA-2omvA:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 6 LEU A 324
ARG A 365
THR A 342
LEU A 341
 None
 1.02A 2dysN-2omvA:
undetectable
2dysW-2omvA:
undetectable		 2dysN-2omvA:
22.56
2dysW-2omvA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 6 LEU A 324
ARG A 365
THR A 342
LEU A 341
 None
 1.03A 2eijA-2omvA:
undetectable
2eijJ-2omvA:
undetectable		 2eijA-2omvA:
22.56
2eijJ-2omvA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 6 LEU A 324
ARG A 365
THR A 342
LEU A 341
 None
 1.01A 2eilA-2omvA:
undetectable
2eilJ-2omvA:
undetectable		 2eilA-2omvA:
22.56
2eilJ-2omvA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 7 VAL A  70
THR A  69
THR A  67
LYS A  58
 None
 1.24A 2kotA-2omvA:
undetectable		 2kotA-2omvA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 12 LEU A 163
THR A 164
ALA A 139
THR A 136
ILE A 135
 None
 1.18A 3a35A-2omvA:
undetectable		 3a35A-2omvA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 12 LEU A 163
THR A 164
ALA A 139
THR A 136
ILE A 135
 None
 1.19A 3a35B-2omvA:
undetectable		 3a35B-2omvA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 12 LEU A 163
THR A 164
ALA A 139
THR A 136
ILE A 135
 None
 1.19A 3a3bA-2omvA:
undetectable		 3a3bA-2omvA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_SALA1505_1
(FERROCHELATASE,
MITOCHONDRIAL)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 9 VAL A 428
SER A 470
LEU A 494
SER A 448
LEU A 462
 None
 1.23A 3w1wA-2omvA:
undetectable
3w1wB-2omvA:
undetectable		 3w1wA-2omvA:
21.74
3w1wB-2omvA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 7 PHE A 193
ASN A 217
LEU A 225
LEU A 212
 None
 0.86A 4ejgC-2omvA:
undetectable		 4ejgC-2omvA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 12 LEU A 404
LEU A 401
ILE A 385
SER A 374
VAL A 357
 None
 1.25A 4f4dB-2omvA:
undetectable		 4f4dB-2omvA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J14_A_X2NA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		6 / 10 ALA A 390
LEU A 412
PHE A 486
VAL A 477
ALA A 402
THR A 399
 None
 1.18A 4j14A-2omvA:
undetectable		 4j14A-2omvA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 12 LEU A 126
ARG A 168
ILE A 132
ILE A 135
LEU A 116
 None
 1.25A 4j24C-2omvA:
undetectable		 4j24C-2omvA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 12 LEU A 126
ARG A 168
ILE A 132
ILE A 135
LEU A 116
 None
 1.20A 4j26B-2omvA:
undetectable		 4j26B-2omvA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 8 LEU A 324
LEU A 346
LEU A 366
ILE A 310
 None
 0.88A 4klaA-2omvA:
undetectable		 4klaA-2omvA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 8 VAL A 357
LEU A 344
LEU A 366
ILE A 351
 None
 0.87A 4lzrA-2omvA:
undetectable		 4lzrA-2omvA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 12 ILE A 222
ASP A 277
LEU A 280
LEU A 263
ILE A 244
 None
 1.08A 4m2xE-2omvA:
undetectable		 4m2xE-2omvA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 12 VAL A 376
ILE A 479
LEU A 398
ALA A 390
LEU A 388
 None
 1.03A 4o1zB-2omvA:
undetectable		 4o1zB-2omvA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 12 VAL A 224
LEU A 234
LEU A 191
LEU A 169
ALA A 181
 None
 1.33A 4rtbA-2omvA:
undetectable		 4rtbA-2omvA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 11 LEU A 410
LEU A 412
ASN A 436
LEU A 398
LEU A 401
 None
 0.91A 4wg0C-2omvA:
undetectable
4wg0D-2omvA:
undetectable
4wg0E-2omvA:
undetectable		 4wg0C-2omvA:
4.76
4wg0D-2omvA:
4.76
4wg0E-2omvA:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 11 LEU A 410
LEU A 412
ASN A 436
LEU A 398
LEU A 401
 None
 0.91A 4wg0E-2omvA:
undetectable
4wg0F-2omvA:
undetectable
4wg0G-2omvA:
undetectable		 4wg0E-2omvA:
4.76
4wg0F-2omvA:
4.76
4wg0G-2omvA:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 11 ASN A 436
LEU A 398
LEU A 401
LEU A 412
LEU A 410
 None
 0.91A 4wg0H-2omvA:
undetectable
4wg0I-2omvA:
undetectable
4wg0J-2omvA:
undetectable		 4wg0H-2omvA:
4.76
4wg0I-2omvA:
4.76
4wg0J-2omvA:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 11 ASN A 436
LEU A 398
LEU A 401
LEU A 412
LEU A 410
 None
 0.90A 4wg0J-2omvA:
undetectable
4wg0K-2omvA:
undetectable
4wg0L-2omvA:
undetectable		 4wg0J-2omvA:
4.76
4wg0K-2omvA:
4.76
4wg0L-2omvA:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 12 LEU A 160
LEU A 144
LEU A 149
MET A 127
ILE A 113
 None
 1.13A 4x1yB-2omvA:
undetectable		 4x1yB-2omvA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 11 LEU A 346
LEU A 363
LEU A 382
ILE A 385
LEU A 344
 None
 1.01A 4zowA-2omvA:
undetectable		 4zowA-2omvA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 7 LEU A 324
ARG A 365
THR A 342
LEU A 341
 None
 0.97A 5b1bA-2omvA:
undetectable
5b1bJ-2omvA:
undetectable		 5b1bA-2omvA:
22.56
5b1bJ-2omvA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		3 / 3 ASN A 128
SER A 106
ARG A  85
 None
 0.95A 5b2qA-2omvA:
undetectable		 5b2qA-2omvA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 6 LEU A 191
LEU A 234
PHE A 193
LEU A 200
 None
 0.97A 5gs4A-2omvA:
undetectable		 5gs4A-2omvA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		5 / 8 ALA A 181
LEU A 188
LEU A 206
LEU A 171
LEU A 169
 None
 1.30A 5jqbA-2omvA:
undetectable
5jqbB-2omvA:
undetectable		 5jqbA-2omvA:
21.78
5jqbB-2omvA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 7 LEU A 324
ARG A 365
THR A 342
LEU A 341
 None
 0.89A 5xdqN-2omvA:
undetectable
5xdqW-2omvA:
undetectable		 5xdqN-2omvA:
22.56
5xdqW-2omvA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 8 LEU A 324
ARG A 365
THR A 342
LEU A 341
 None
 0.90A 5xdxN-2omvA:
undetectable
5xdxW-2omvA:
undetectable		 5xdxN-2omvA:
22.56
5xdxW-2omvA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 8 LEU A 324
ARG A 365
THR A 342
LEU A 341
 None
 0.87A 5zcpN-2omvA:
undetectable
5zcpW-2omvA:
undetectable		 5zcpN-2omvA:
22.56
5zcpW-2omvA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 5 THR A 148
ARG A 168
THR A  80
GLN A  82
 None
 1.39A 6ectA-2omvA:
undetectable		 6ectA-2omvA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		4 / 5 THR A 148
ARG A 168
THR A  80
GLN A  82
 None
 1.41A 6ecxA-2omvA:
undetectable		 6ecxA-2omvA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 2omv INTERNALIN-A
(Listeria
monocytogenes) 		3 / 3 ASP A 353
SER A 336
SER A 359
 None
 0.70A 6mxtA-2omvA:
undetectable		 6mxtA-2omvA:
21.37