SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2onk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 147
LEU A   3
MET A  22
VAL A  18
VAL A 183
 None
 1.20A 1hrkA-2onkA:
undetectable		 1hrkA-2onkA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 147
LEU A   3
MET A  22
VAL A  18
VAL A 183
 None
 1.25A 1hrkB-2onkA:
undetectable		 1hrkB-2onkA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 ILE A  72
LEU A  57
MET A   1
GLY A  23
 None
 1.00A 1os6A-2onkA:
undetectable		 1os6A-2onkA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		4 / 5 ALA A 111
TYR A  88
ILE A  91
ASP A 104
 None
 1.24A 1upfA-2onkA:
undetectable		 1upfA-2onkA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		4 / 5 ALA A 111
TYR A  88
ILE A  91
ASP A 104
 None
 1.04A 1upfC-2onkA:
undetectable		 1upfC-2onkA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
PERMEASE PROTEIN
(Archaeoglobus
fulgidus) 		4 / 5 LEU C 216
PRO C 231
VAL C 232
ILE C 217
 None
 1.01A 2aoiB-2onkC:
undetectable		 2aoiB-2onkC:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 147
LEU A   3
MET A  22
VAL A  18
VAL A 183
 None
 1.13A 2hrcB-2onkA:
undetectable		 2hrcB-2onkA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 147
LEU A   3
MET A  22
VAL A  18
VAL A 183
 None
 1.28A 2qd4B-2onkA:
undetectable		 2qd4B-2onkA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDM_B_AGGB1462_1
(INTEGRIN ALPHA-IIB
INTEGRIN BETA-3)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
PERMEASE PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 TYR C  55
LEU C  52
SER C 139
SER C 192
ALA C  58
 None
 1.49A 2vdmA-2onkC:
undetectable
2vdmB-2onkC:
undetectable		 2vdmA-2onkC:
23.31
2vdmB-2onkC:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 ILE A  44
LEU A  41
LEU A 150
VAL A 172
 None
 0.97A 3r9vA-2onkA:
undetectable
3r9vB-2onkA:
undetectable		 3r9vA-2onkA:
22.40
3r9vB-2onkA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		4 / 8 ILE A  72
LEU A  57
MET A   1
GLY A  23
 None
 0.99A 3selX-2onkA:
undetectable		 3selX-2onkA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		4 / 6 ILE A  72
LEU A  57
MET A   1
GLY A  23
 None
 1.01A 3sj1X-2onkA:
undetectable		 3sj1X-2onkA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 147
LEU A   3
MET A  22
VAL A  18
VAL A 183
 None
 1.26A 3w1wA-2onkA:
undetectable		 3w1wA-2onkA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 ILE A  72
LEU A  57
MET A   1
GLY A  23
 None
 1.03A 4hajA-2onkA:
undetectable		 4hajA-2onkA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		4 / 7 ILE A  72
LEU A  57
MET A   1
GLY A  23
 None
 1.01A 4hbfA-2onkA:
undetectable		 4hbfA-2onkA:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
PERMEASE PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 PRO C 210
MET C 211
TYR C 209
 None
 0.92A 4qa2B-2onkC:
undetectable		 4qa2B-2onkC:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
PERMEASE PROTEIN
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		4 / 7 PHE A  82
LEU A  85
THR C 164
VAL C 176
 None
 1.03A 4wnvD-2onkA:
undetectable		 4wnvD-2onkA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
PERMEASE PROTEIN
(Archaeoglobus
fulgidus;
Archaeoglobus
fulgidus) 		5 / 12 GLY A  73
GLY A  71
GLY C 166
LEU C 165
LEU A 148
 None
 1.08A 5c0oE-2onkA:
undetectable		 5c0oE-2onkA:
25.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		4 / 6 TYR A  88
ILE A 116
VAL A 107
ALA A 111
 None
 0.82A 5cu6A-2onkA:
undetectable		 5cu6A-2onkA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 ILE A 180
MET A   1
ASP A 195
 None
 0.74A 5h2uA-2onkA:
undetectable		 5h2uA-2onkA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
ATP-BINDING PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 LYS A   4
LEU A 181
ILE A 205
 None
 0.77A 5kc0A-2onkA:
undetectable		 5kc0A-2onkA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
PERMEASE PROTEIN
(Archaeoglobus
fulgidus) 		5 / 12 LEU C 178
PHE C 151
ILE C 185
ALA C 189
THR C  62
 None
 1.06A 5veuB-2onkC:
undetectable		 5veuB-2onkC:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 2onk MOLYBDATE/TUNGSTATE
ABC TRANSPORTER,
PERMEASE PROTEIN
(Archaeoglobus
fulgidus) 		3 / 3 ARG C 195
ILE C 142
SER C 139
 None
 0.86A 5zw2A-2onkC:
undetectable		 5zw2A-2onkC:
21.89