SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2onu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WRL_F_TFPF211_1 (TROPONIN C, SLOW SKELETAL AND CARDIAC MUSCLES)	2onu	UBIQUITIN-CONJUGATIN G ENZYME, PUTATIVE (Plasmodium falciparum)	4 / 7	LEU A 110 PHE A 105 PHE A 35 LEU A 71	None	0.98A	1wrlE-2onuA: undetectable 1wrlF-2onuA: undetectable	1wrlE-2onuA: 18.79 1wrlF-2onuA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IW1_A_ASDA1223_1 (CYTOCHROME P450 CYP125)	2onu	UBIQUITIN-CONJUGATIN G ENZYME, PUTATIVE (Plasmodium falciparum)	5 / 12	ILE A 15 PHE A 35 VAL A 33 ILE A 65 VAL A 52	None	1.17A	3iw1A-2onuA: undetectable	3iw1A-2onuA: 16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N6D_B_H4BB600_1 (NITRIC OXIDE SYNTHASE)	2onu	UBIQUITIN-CONJUGATIN G ENZYME, PUTATIVE (Plasmodium falciparum)	4 / 6	TRP A 48 PHE A 35 VAL A 76 PRO A 38	None	1.29A	3n6dA-2onuA: undetectable 3n6dB-2onuA: 0.0	3n6dA-2onuA: 16.22 3n6dB-2onuA: 16.22