SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ooc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXY_A_SAMA6734_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 2ooc HISTIDINE
PHOSPHOTRANSFERASE
(Caulobacter
vibrioides) 		5 / 12 VAL A  65
ALA A  62
GLY A  60
ALA A  41
LEU A  30
 None
 1.15A 3qxyA-2oocA:
undetectable		 3qxyA-2oocA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_A_SAMA484_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 2ooc HISTIDINE
PHOSPHOTRANSFERASE
(Caulobacter
vibrioides) 		5 / 11 VAL A  65
ALA A  62
GLY A  60
ALA A  41
LEU A  30
 None
 1.10A 3rc0A-2oocA:
undetectable		 3rc0A-2oocA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RC0_B_SAMB480_0
(N-LYSINE
METHYLTRANSFERASE
SETD6)		 2ooc HISTIDINE
PHOSPHOTRANSFERASE
(Caulobacter
vibrioides) 		5 / 12 VAL A  65
ALA A  62
GLY A  60
ALA A  41
LEU A  30
 None
 1.12A 3rc0B-2oocA:
undetectable		 3rc0B-2oocA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ooc HISTIDINE
PHOSPHOTRANSFERASE
(Caulobacter
vibrioides) 		5 / 12 LEU A  30
LEU A  95
VAL A  65
GLY A  66
ALA A  67
 None
 1.07A 3rr3C-2oocA:
undetectable		 3rr3C-2oocA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ooc HISTIDINE
PHOSPHOTRANSFERASE
(Caulobacter
vibrioides) 		5 / 12 LEU A  30
LEU A  95
VAL A  65
GLY A  66
ALA A  67
 None
 1.07A 3rr3D-2oocA:
undetectable		 3rr3D-2oocA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ooc HISTIDINE
PHOSPHOTRANSFERASE
(Caulobacter
vibrioides) 		4 / 5 ARG A  76
VAL A  87
LEU A  84
SER A  83
 None
None
PG4  A 113 ( 4.7A)
GOL  A 114 (-3.8A)
 1.34A 4e1gA-2oocA:
undetectable		 4e1gA-2oocA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 2ooc HISTIDINE
PHOSPHOTRANSFERASE
(Caulobacter
vibrioides) 		5 / 12 GLY A  50
PRO A  49
VAL A  58
LEU A  44
VAL A  87
 None
 0.98A 4gc9A-2oocA:
undetectable		 4gc9A-2oocA:
17.31