SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2opg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 2opg MULTIPLE PDZ DOMAIN
PROTEIN
(Homo
sapiens) 		5 / 12 PRO A1701
THR A1700
ILE A1683
LEU A1706
ILE A1677
 None
 1.14A 3a50E-2opgA:
undetectable		 3a50E-2opgA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 2opg MULTIPLE PDZ DOMAIN
PROTEIN
(Homo
sapiens) 		5 / 12 ALA A1693
GLY A1652
GLY A1645
LEU A1650
ALA A1688
 None
 1.09A 4lg1C-2opgA:
undetectable		 4lg1C-2opgA:
20.72