SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2opk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 2opk HYPOTHETICAL PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 VAL A  58
TRP A  81
TRP A  55
 None
 1.04A 1c4dA-2opkA:
undetectable
1c4dB-2opkA:
undetectable		 1c4dA-2opkA:
13.98
1c4dB-2opkA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 2opk HYPOTHETICAL PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 3 VAL A  84
TRP A  55
TRP A  81
 None
 1.26A 1c4dA-2opkA:
undetectable
1c4dB-2opkA:
undetectable		 1c4dA-2opkA:
13.98
1c4dB-2opkA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 2opk HYPOTHETICAL PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 4 VAL A 106
TRP A 103
TRP A  55
 None
UNL  A 112 (-3.5A)
None
 0.73A 1gmkA-2opkA:
undetectable
1gmkB-2opkA:
undetectable		 1gmkA-2opkA:
13.98
1gmkB-2opkA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 2opk HYPOTHETICAL PROTEIN
(Cupriavidus
pinatubonensis) 		3 / 4 VAL A 106
TRP A 103
TRP A  55
 None
UNL  A 112 (-3.5A)
None
 0.81A 1gmkC-2opkA:
undetectable
1gmkD-2opkA:
undetectable		 1gmkC-2opkA:
13.98
1gmkD-2opkA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 2opk HYPOTHETICAL PROTEIN
(Cupriavidus
pinatubonensis) 		4 / 8 MET A  76
ALA A  63
GLY A  64
ILE A  65
 None
 0.82A 2zm9A-2opkA:
undetectable		 2zm9A-2opkA:
15.80