SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2opt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 THR A 165
LEU A 162
GLY A 160
TYR A 158
 None
 1.35A 1gtiC-2optA:
undetectable		 1gtiC-2optA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 ARG A 128
LEU A  44
ALA A  40
LEU A  49
 None
 1.00A 1ukbA-2optA:
undetectable		 1ukbA-2optA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 8 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.68A 1v54C-2optA:
3.1
1v54J-2optA:
undetectable		 1v54C-2optA:
23.19
1v54J-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 8 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.67A 1v54P-2optA:
3.1
1v54W-2optA:
undetectable		 1v54P-2optA:
23.19
1v54W-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.68A 1v55P-2optA:
3.1
1v55W-2optA:
undetectable		 1v55P-2optA:
23.19
1v55W-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 8 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.70A 2dyrC-2optA:
3.2
2dyrJ-2optA:
undetectable		 2dyrC-2optA:
23.19
2dyrJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 8 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.65A 2dyrP-2optA:
3.1
2dyrW-2optA:
undetectable		 2dyrP-2optA:
23.19
2dyrW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.70A 2dysC-2optA:
3.0
2dysJ-2optA:
undetectable		 2dysC-2optA:
23.19
2dysJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.68A 2dysP-2optA:
3.2
2dysW-2optA:
undetectable		 2dysP-2optA:
23.19
2dysW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.67A 2eijC-2optA:
3.1
2eijJ-2optA:
undetectable		 2eijC-2optA:
23.19
2eijJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.68A 2eijP-2optA:
3.0
2eijW-2optA:
undetectable		 2eijP-2optA:
23.19
2eijW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 8 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.67A 2eikP-2optA:
3.2
2eikW-2optA:
undetectable		 2eikP-2optA:
23.19
2eikW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 8 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.66A 2eilC-2optA:
2.9
2eilJ-2optA:
undetectable		 2eilC-2optA:
23.19
2eilJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 8 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.66A 2eilP-2optA:
3.1
2eilW-2optA:
undetectable		 2eilP-2optA:
23.19
2eilW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.75A 2eimC-2optA:
2.9
2eimJ-2optA:
undetectable		 2eimC-2optA:
23.19
2eimJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.69A 2eimP-2optA:
2.9
2eimW-2optA:
undetectable		 2eimP-2optA:
23.19
2eimW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.70A 2einC-2optA:
2.9
2einJ-2optA:
undetectable		 2einC-2optA:
23.19
2einJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.67A 2einP-2optA:
3.1
2einW-2optA:
undetectable		 2einP-2optA:
23.19
2einW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 LEU A 163
ARG A 225
GLU A 102
ARG A 109
 None
 0.79A 2jn3A-2optA:
undetectable		 2jn3A-2optA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 MET A 143
MET A 139
MET A 107
LEU A 146
 None
 1.20A 2oz7A-2optA:
undetectable		 2oz7A-2optA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.72A 2zxwC-2optA:
3.1
2zxwJ-2optA:
undetectable		 2zxwC-2optA:
23.19
2zxwJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.71A 2zxwP-2optA:
3.1
2zxwW-2optA:
undetectable		 2zxwP-2optA:
23.19
2zxwW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.60A 3abkP-2optA:
3.1
3abkW-2optA:
undetectable		 3abkP-2optA:
23.19
3abkW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.61A 3ag1C-2optA:
3.1
3ag1J-2optA:
undetectable		 3ag1C-2optA:
23.19
3ag1J-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.72A 3ag2C-2optA:
3.1		 3ag2C-2optA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.71A 3ag2P-2optA:
3.1
3ag2W-2optA:
undetectable		 3ag2P-2optA:
23.19
3ag2W-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 8 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.67A 3ag4C-2optA:
3.1
3ag4J-2optA:
undetectable		 3ag4C-2optA:
23.19
3ag4J-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.64A 3ag4P-2optA:
3.1
3ag4W-2optA:
undetectable		 3ag4P-2optA:
23.19
3ag4W-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.68A 3asnC-2optA:
3.0
3asnJ-2optA:
undetectable		 3asnC-2optA:
23.19
3asnJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.66A 3asnP-2optA:
3.1
3asnW-2optA:
undetectable		 3asnP-2optA:
23.19
3asnW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 8 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.72A 3asoC-2optA:
3.1
3asoJ-2optA:
undetectable		 3asoC-2optA:
23.19
3asoJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.69A 3asoP-2optA:
3.1
3asoW-2optA:
undetectable		 3asoP-2optA:
23.19
3asoW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		5 / 11 GLU A 102
LEU A 230
ARG A 109
GLY A 236
LEU A 238
 None
 1.25A 3hm1B-2optA:
undetectable		 3hm1B-2optA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 8 GLY A 159
LEU A 162
LEU A 163
ILE A 233
 None
 0.86A 3nbqC-2optA:
undetectable		 3nbqC-2optA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 LEU A  57
SER A  53
ARG A  56
LEU A  68
 None
 1.07A 3ravA-2optA:
2.7		 3ravA-2optA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		5 / 11 GLU A 102
LEU A 230
ARG A 109
GLY A 236
LEU A 238
 None
 1.26A 3uudA-2optA:
undetectable		 3uudA-2optA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.68A 3wg7C-2optA:
3.1
3wg7J-2optA:
undetectable		 3wg7C-2optA:
23.19
3wg7J-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.69A 3wg7P-2optA:
3.1
3wg7W-2optA:
undetectable		 3wg7P-2optA:
23.19
3wg7W-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.66A 3x2qC-2optA:
3.1
3x2qJ-2optA:
undetectable		 3x2qC-2optA:
23.19
3x2qJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		5 / 12 GLU A 102
LEU A 230
ARG A 109
GLY A 236
LEU A 238
 None
 1.28A 4j26A-2optA:
undetectable		 4j26A-2optA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.73A 5b1aC-2optA:
3.1
5b1aJ-2optA:
undetectable		 5b1aC-2optA:
23.19
5b1aJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.71A 5b1aP-2optA:
3.1
5b1aW-2optA:
undetectable		 5b1aP-2optA:
23.19
5b1aW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.71A 5b3sC-2optA:
3.1
5b3sJ-2optA:
undetectable		 5b3sC-2optA:
23.19
5b3sJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.75A 5b3sP-2optA:
3.1		 5b3sP-2optA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXG_B_ESTB601_1
(ESTROGEN RECEPTOR)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		5 / 11 GLU A 102
LEU A 230
ARG A 109
GLY A 236
LEU A 238
 None
 1.24A 5dxgB-2optA:
2.9		 5dxgB-2optA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		5 / 12 PHE A 115
MET A 114
VAL A  86
LEU A 111
PHE A  83
 None
 1.23A 5im2A-2optA:
undetectable		 5im2A-2optA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.69A 5iy5C-2optA:
3.2
5iy5J-2optA:
undetectable		 5iy5C-2optA:
23.30
5iy5J-2optA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 5 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.71A 5iy5P-2optA:
2.9
5iy5W-2optA:
undetectable		 5iy5P-2optA:
23.30
5iy5W-2optA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.65A 5w97C-2optA:
3.1
5w97J-2optA:
undetectable		 5w97C-2optA:
23.19
5w97J-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 6 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.62A 5x19P-2optA:
3.0		 5x19P-2optA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		3 / 3 ARG A  75
PHE A  83
LEU A  49
 None
 0.60A 5x1bC-2optA:
3.0		 5x1bC-2optA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 5 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.67A 5x1bP-2optA:
3.1		 5x1bP-2optA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 5 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.61A 5x1fC-2optA:
3.2
5x1fJ-2optA:
undetectable		 5x1fC-2optA:
23.19
5x1fJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.66A 5x1fP-2optA:
3.1
5x1fW-2optA:
undetectable		 5x1fP-2optA:
23.19
5x1fW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 5 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.65A 5xdxC-2optA:
3.1
5xdxJ-2optA:
undetectable		 5xdxC-2optA:
23.21
5xdxJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 5 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.71A 5xdxP-2optA:
2.9
5xdxW-2optA:
undetectable		 5xdxP-2optA:
23.21
5xdxW-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.68A 5z84C-2optA:
3.1
5z84J-2optA:
undetectable		 5z84C-2optA:
23.19
5z84J-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.71A 5z85C-2optA:
3.1
5z85J-2optA:
undetectable		 5z85C-2optA:
23.19
5z85J-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.65A 5zcoC-2optA:
3.1
5zcoJ-2optA:
undetectable		 5zcoC-2optA:
23.19
5zcoJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		4 / 7 ARG A  75
LEU A  79
PHE A  83
LEU A  49
 None
 0.69A 5zcqC-2optA:
3.1
5zcqJ-2optA:
undetectable		 5zcqC-2optA:
23.19
5zcqJ-2optA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2opt ACTII PROTEIN
(Streptomyces
coelicolor) 		3 / 3 ARG A  75
LEU A  79
PHE A  83
 None
 0.49A 6nknP-2optA:
3.0		 6nknP-2optA:
23.19