SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 2oq1 TYROSINE-PROTEIN
KINASE ZAP-70
(Homo
sapiens) 		4 / 8 TYR A 180
GLY A 187
ASP A 186
TYR A 211
 None
 0.97A 1rmtC-2oq1A:
undetectable		 1rmtC-2oq1A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0H_B_ACHB1289_0
(FICOLIN-2)		 2oq1 TYROSINE-PROTEIN
KINASE ZAP-70
(Homo
sapiens) 		4 / 4 ARG A  43
ASP A 246
THR A 229
LYS A 244
 None
 1.30A 2j0hB-2oq1A:
0.0		 2j0hB-2oq1A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0H_E_ACHE1289_0
(FICOLIN-2)		 2oq1 TYROSINE-PROTEIN
KINASE ZAP-70
(Homo
sapiens) 		4 / 4 ARG A  43
ASP A 246
THR A 229
LYS A 244
 None
 1.18A 2j0hE-2oq1A:
0.0		 2j0hE-2oq1A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_A_SC2A1290_1
(FICOLIN-2)		 2oq1 TYROSINE-PROTEIN
KINASE ZAP-70
(Homo
sapiens) 		4 / 5 ASP A   5
LEU A  45
GLY A  46
ARG A 121
 None
 1.17A 2j2pA-2oq1A:
undetectable
2j2pB-2oq1A:
undetectable		 2j2pA-2oq1A:
19.25
2j2pB-2oq1A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1289_1
(FICOLIN-2)		 2oq1 TYROSINE-PROTEIN
KINASE ZAP-70
(Homo
sapiens) 		4 / 4 ARG A  43
ASP A 246
THR A 229
LYS A 244
 None
 1.23A 2j2pB-2oq1A:
0.0		 2j2pB-2oq1A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 2oq1 TYROSINE-PROTEIN
KINASE ZAP-70
(Homo
sapiens) 		4 / 6 ARG A  43
ASP A 246
THR A 229
LYS A 244
 None
 1.19A 2j2pE-2oq1A:
undetectable
2j2pF-2oq1A:
undetectable		 2j2pE-2oq1A:
19.25
2j2pF-2oq1A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1291_1
(FICOLIN-2)		 2oq1 TYROSINE-PROTEIN
KINASE ZAP-70
(Homo
sapiens) 		4 / 4 ASP A   5
LEU A  45
GLY A  46
ARG A 121
 None
 1.19A 2j2pD-2oq1A:
0.0
2j2pE-2oq1A:
0.0		 2j2pD-2oq1A:
19.25
2j2pE-2oq1A:
19.25