SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 6 ASN A 207
GLN A  84
THR A 223
PRO A 225
 None
 1.50A 2ez7A-2oq2A:
undetectable		 2ez7A-2oq2A:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_2
(PHOSPHOLIPASE A2)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 8 LYS A  95
ASN A 202
PRO A  30
TRP A 190
 None
 1.13A 3bjwD-2oq2A:
undetectable		 3bjwD-2oq2A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 156
TYR A  68
LEU A  55
 None
 0.77A 3keeB-2oq2A:
undetectable		 3keeB-2oq2A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 156
TYR A  68
LEU A  55
 None
 0.77A 3sueB-2oq2A:
undetectable		 3sueB-2oq2A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 GLN A  46
GLY A  51
GLY A  54
SER A 216
ALA A  49
 None
A3P  A 999 (-3.5A)
A3P  A 999 (-3.1A)
A3P  A 999 ( 4.6A)
A3P  A 999 (-3.4A)
 1.22A 3t7sB-2oq2A:
2.3		 3t7sB-2oq2A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 8 GLU A 208
ILE A 104
VAL A 106
PHE A  75
 None
 0.88A 4dx7B-2oq2A:
undetectable		 4dx7B-2oq2A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F84_A_SAMA501_0
(GERANYL DIPHOSPHATE
2-C-METHYLTRANSFERAS
E)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		5 / 12 GLY A  54
GLY A 158
VAL A  56
THR A  53
LEU A  52
 A3P  A 999 (-3.1A)
A3P  A 999 (-3.2A)
None
A3P  A 999 ( 4.6A)
None
 1.21A 4f84A-2oq2A:
undetectable		 4f84A-2oq2A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA501_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 126
LYS A 129
ASP A 130
LYS A 133
 None
 1.48A 4i90A-2oq2A:
0.0		 4i90A-2oq2A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 5 ILE A  76
PHE A 256
HIS A  81
ASP A 135
 A3P  A 999 (-3.9A)
None
None
None
 1.43A 4rzvB-2oq2A:
undetectable		 4rzvB-2oq2A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 5 GLY A  54
PRO A  71
THR A  57
THR A  48
 A3P  A 999 (-3.1A)
None
None
A3P  A 999 (-3.6A)
 1.01A 5h5fA-2oq2A:
2.0		 5h5fA-2oq2A:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 5 GLU A 232
GLY A  51
ARG A 236
GLY A 218
 None
A3P  A 999 (-3.5A)
A3P  A 999 (-3.1A)
None
 1.09A 5kprA-2oq2A:
undetectable		 5kprA-2oq2A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 4 GLU A  32
PRO A  30
ILE A  33
LEU A  27
 None
 1.26A 5m45A-2oq2A:
undetectable		 5m45A-2oq2A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 4 GLU A  32
PRO A  30
ILE A  33
LEU A  27
 None
 1.32A 5m45D-2oq2A:
undetectable		 5m45D-2oq2A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 4 GLU A  32
PRO A  30
ILE A  33
LEU A  27
 None
 1.26A 5m45G-2oq2A:
undetectable		 5m45G-2oq2A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 4 GLU A  32
PRO A  30
ILE A  33
LEU A  27
 None
 1.33A 5m45J-2oq2A:
undetectable		 5m45J-2oq2A:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		3 / 3 SER A  62
LYS A  63
SER A  65
 None
 0.70A 6az3P-2oq2A:
undetectable		 6az3P-2oq2A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 2oq2 PHOSPHOADENOSINE
PHOSPHOSULFATE
REDUCTASE
(Saccharomyces
cerevisiae) 		4 / 4 ILE A 247
LEU A  74
HIS A 144
ALA A 146
 None
 1.01A 6ck2C-2oq2A:
undetectable
6ck2D-2oq2A:
undetectable		 6ck2C-2oq2A:
7.92
6ck2D-2oq2A:
10.83