SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oq3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 2oq3 MANNITOL-SPECIFIC
CRYPTIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		5 / 11 SER A  13
LEU A  83
THR A  82
ILE A 127
ILE A 144
 None
 1.16A 1pkvA-2oq3A:
undetectable
1pkvB-2oq3A:
undetectable		 1pkvA-2oq3A:
19.33
1pkvB-2oq3A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 2oq3 MANNITOL-SPECIFIC
CRYPTIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 SER A  28
LEU A 100
LEU A  84
ASP A  26
 None
 1.06A 2j2pA-2oq3A:
undetectable
2j2pB-2oq3A:
undetectable		 2j2pA-2oq3A:
20.10
2j2pB-2oq3A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 2oq3 MANNITOL-SPECIFIC
CRYPTIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		3 / 3 PRO A   8
LEU A 103
SER A  31
 None
 0.81A 5fsaB-2oq3A:
undetectable		 5fsaB-2oq3A:
16.74