SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oqh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4003_1
(SERUM ALBUMIN)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 9 LEU A 169
VAL A 179
GLY A 177
ALA A 210
LEU A 214
 None
 1.14A 1e7bA-2oqhA:
undetectable		 1e7bA-2oqhA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 12 GLY A  48
ILE A  97
GLY A 275
GLY A 276
ILE A 277
 None
 0.84A 1hxbA-2oqhA:
undetectable		 1hxbA-2oqhA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1868_0
(FPRA)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		3 / 3 ALA A 308
HIS A 309
VAL A 312
 None
 0.50A 1lqtB-2oqhA:
undetectable		 1lqtB-2oqhA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1425_0
(FPRA)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		3 / 3 ALA A 308
HIS A 309
VAL A 312
 None
 0.49A 1lquB-2oqhA:
undetectable		 1lquB-2oqhA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 12 TYR A 272
LEU A 120
VAL A 116
ALA A 305
ALA A 308
 None
 1.25A 1q23A-2oqhA:
undetectable
1q23B-2oqhA:
undetectable		 1q23A-2oqhA:
18.68
1q23B-2oqhA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 11 VAL A 158
GLU A 153
ALA A 152
ILE A 181
ALA A 139
 None
 1.33A 2admB-2oqhA:
undetectable		 2admB-2oqhA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 8 ASP A 197
TYR A 221
HIS A 297
HIS A 268
 None
 1.19A 2bteA-2oqhA:
undetectable		 2bteA-2oqhA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 8 ASP A 197
TYR A 221
HIS A 297
HIS A 268
 None
 1.21A 2bteD-2oqhA:
undetectable		 2bteD-2oqhA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 9 TYR A 221
LEU A 283
HIS A 268
ARG A 321
LEU A 319
 None
 1.26A 2bxeA-2oqhA:
undetectable		 2bxeA-2oqhA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 7 ASP A 197
TYR A 221
HIS A 297
HIS A 268
 None
 1.13A 2bytA-2oqhA:
undetectable		 2bytA-2oqhA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 7 ASP A 197
TYR A 221
HIS A 297
HIS A 268
 None
 1.13A 2bytD-2oqhA:
undetectable		 2bytD-2oqhA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 6 VAL A 318
ARG A 321
LEU A 296
HIS A 268
 None
 1.24A 2f8dA-2oqhA:
undetectable		 2f8dA-2oqhA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 6 LEU A 338
ILE A 304
VAL A 355
ALA A 307
 None
 1.07A 2j5mA-2oqhA:
undetectable		 2j5mA-2oqhA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 8 ASP A 197
TYR A 221
HIS A 297
HIS A 268
 None
 1.30A 2v0gA-2oqhA:
undetectable		 2v0gA-2oqhA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 12 ILE A 334
LEU A  15
ASP A 333
GLY A 303
ILE A 304
 None
 1.05A 2ycjA-2oqhA:
10.3		 2ycjA-2oqhA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 12 GLY A 211
LEU A 217
ASP A 206
LEU A 222
LEU A 243
 None
 1.39A 3cjtK-2oqhA:
3.6		 3cjtK-2oqhA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_0
(UNCHARACTERIZED
PROTEIN RPA2492)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 12 TYR A 221
PRO A 129
GLY A 293
LEU A 292
HIS A 268
 None
 1.18A 3e23A-2oqhA:
undetectable		 3e23A-2oqhA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 5 ASP A 218
ILE A 241
VAL A 196
THR A 131
 None
 1.16A 3eigA-2oqhA:
undetectable		 3eigA-2oqhA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		3 / 3 VAL A 357
VAL A 355
TRP A  47
 None
 0.88A 3l8lA-2oqhA:
undetectable
3l8lB-2oqhA:
undetectable		 3l8lA-2oqhA:
4.10
3l8lB-2oqhA:
2.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_B_KKKB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 12 PHE A  78
TRP A 105
ALA A  64
ILE A   5
MET A 108
 None
 1.50A 3ld6B-2oqhA:
undetectable		 3ld6B-2oqhA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 10 VAL A  60
GLY A  93
ALA A  96
ALA A  95
THR A  34
 None
 1.17A 3ucjA-2oqhA:
undetectable		 3ucjA-2oqhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 10 VAL A  60
GLY A  93
ALA A  96
ALA A  95
THR A  34
 None
 1.19A 3ucjB-2oqhA:
undetectable		 3ucjB-2oqhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 12 ARG A  61
ASN A  14
ILE A 334
VAL A  35
ILE A 304
 None
 0.98A 4aztA-2oqhA:
2.6		 4aztA-2oqhA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 12 ALA A 210
ASP A 197
PRO A 225
GLY A 171
THR A 135
 None
 1.33A 5hfjG-2oqhA:
undetectable		 5hfjG-2oqhA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 5 VAL A 312
THR A 280
ASP A 270
LEU A 296
 None
 1.19A 5m0iB-2oqhA:
undetectable		 5m0iB-2oqhA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		3 / 3 GLU A 220
ARG A 195
TYR A 221
 None
 0.46A 5trqB-2oqhA:
undetectable		 5trqB-2oqhA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 7 ASN A 246
ASP A 224
GLY A 171
ASN A 199
 None
 1.06A 5x7pA-2oqhA:
3.2		 5x7pA-2oqhA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCN_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		5 / 12 GLY A 171
LEU A 194
VAL A 185
ILE A 181
MET A 151
 None
 0.93A 5ycnA-2oqhA:
undetectable		 5ycnA-2oqhA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 2oqh PUTATIVE ISOMERASE
(Streptomyces
coelicolor) 		4 / 5 VAL A 249
LEU A 283
VAL A 318
LEU A 296
 None
 0.98A 6bqgA-2oqhA:
undetectable		 6bqgA-2oqhA:
11.70