SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oqk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AYF_A_C7HA402_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	2oqk	PUTATIVE TRANSLATION INITIATION FACTOR EIF-1A (Cryptosporidium parvum)	4 / 5	GLY A 107 TYR A 95 TYR A 35 GLY A 36	None	0.83A	5ayfA-2oqkA: undetectable	5ayfA-2oqkA: 19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KC4_E_RBFE201_2 (RIBOFLAVIN TRANSPORTER RIBU)	2oqk	PUTATIVE TRANSLATION INITIATION FACTOR EIF-1A (Cryptosporidium parvum)	3 / 3	LYS A 88 ASP A 86 ILE A 91	None	0.68A	5kc4E-2oqkA: undetectable	5kc4E-2oqkA: 19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWD_D_GLYD713_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	2oqk	PUTATIVE TRANSLATION INITIATION FACTOR EIF-1A (Cryptosporidium parvum)	3 / 3	ARG A 46 HIS A 60 ARG A 82	SO4 A 201 (-3.9A) SO4 A 201 (-4.4A) SO4 A 201 (-3.0A)	0.67A	6dwdD-2oqkA: undetectable	6dwdD-2oqkA: 12.31