SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oqr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OGP_A_017A200_1 (FIV PROTEASE)	2oqr	SENSORY TRANSDUCTION PROTEIN REGX3 (Mycobacterium tuberculosis)	5 / 9	GLY A 45 ALA A 46 ASP A 47 ILE A 48 LEU A 5	None	0.91A	3ogpA-2oqrA: undetectable	3ogpA-2oqrA: 18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OGP_B_017B200_2 (FIV PROTEASE)	2oqr	SENSORY TRANSDUCTION PROTEIN REGX3 (Mycobacterium tuberculosis)	5 / 9	GLY A 45 ALA A 46 ASP A 47 ILE A 48 LEU A 5	None	0.89A	3ogpB-2oqrA: undetectable	3ogpB-2oqrA: 18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBR_A_ACTA608_0 (SERUM ALBUMIN)	2oqr	SENSORY TRANSDUCTION PROTEIN REGX3 (Mycobacterium tuberculosis)	3 / 3	LYS A 199 ARG A 200 HIS A 197	None	0.86A	4zbrA-2oqrA: undetectable	4zbrA-2oqrA: 17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Z_A_BHAA201_0 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	2oqr	SENSORY TRANSDUCTION PROTEIN REGX3 (Mycobacterium tuberculosis)	4 / 6	LEU A 51 VAL A 49 LEU A 5 ARG A 70	None	0.90A	5x7zA-2oqrA: 3.7	5x7zA-2oqrA: 23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EU9_B_REAB601_1 (RETINOIC ACID RECEPTOR)	2oqr	SENSORY TRANSDUCTION PROTEIN REGX3 (Mycobacterium tuberculosis)	5 / 10	VAL A 49 LEU A 50 LEU A 55 GLY A 45 GLY A 34	None	1.18A	6eu9B-2oqrA: undetectable	6eu9B-2oqrA: 17.39

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3OGP_A_017A200_1","FIV PROTEASE","2oqr","SENSORY TRANSDUCTION PROTEIN REGX3","Mycobacterium tuberculosis",5,"GLY A  45;ALA A  46;ASP A  47;ILE A  48;LEU A   5","None","0.91A","3ogpA-2oqrA:undetectable","3ogpA-2oqrA:18.22"],["3OGP_B_017B200_2","FIV PROTEASE","2oqr","SENSORY TRANSDUCTION PROTEIN REGX3","Mycobacterium tuberculosis",5,"GLY A  45;ALA A  46;ASP A  47;ILE A  48;LEU A   5","None","0.89A","3ogpB-2oqrA:undetectable","3ogpB-2oqrA:18.22"],["4ZBR_A_ACTA608_0","SERUM ALBUMIN","2oqr","SENSORY TRANSDUCTION PROTEIN REGX3","Mycobacterium tuberculosis",3,"LYS A 199;ARG A 200;HIS A 197","None","0.86A","4zbrA-2oqrA:undetectable","4zbrA-2oqrA:17.99"],["5X7Z_A_BHAA201_0","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887","2oqr","SENSORY TRANSDUCTION PROTEIN REGX3","Mycobacterium tuberculosis",4,"LEU A  51;VAL A  49;LEU A   5;ARG A  70","None","0.90A","5x7zA-2oqrA:3.7","5x7zA-2oqrA:23.98"],["6EU9_B_REAB601_1","RETINOIC ACID RECEPTOR","2oqr","SENSORY TRANSDUCTION PROTEIN REGX3","Mycobacterium tuberculosis",5,"VAL A  49;LEU A  50;LEU A  55;GLY A  45;GLY A  34","None","1.18A","6eu9B-2oqrA:undetectable","6eu9B-2oqrA:17.39"]]