SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2oqz SORTASE B
(Bacillus
anthracis) 		4 / 6 ASN A 102
ILE A 192
ASN A 134
ASN A 126
 CS4  A 233 ( 4.1A)
None
None
None
 1.21A 1h7xA-2oqzA:
undetectable		 1h7xA-2oqzA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2oqz SORTASE B
(Bacillus
anthracis) 		4 / 6 ASN A 102
ILE A 192
ASN A 134
ASN A 126
 CS4  A 233 ( 4.1A)
None
None
None
 1.21A 1h7xB-2oqzA:
undetectable		 1h7xB-2oqzA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2oqz SORTASE B
(Bacillus
anthracis) 		4 / 6 ASN A 102
ILE A 192
ASN A 134
ASN A 126
 CS4  A 233 ( 4.1A)
None
None
None
 1.20A 1h7xC-2oqzA:
undetectable		 1h7xC-2oqzA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2oqz SORTASE B
(Bacillus
anthracis) 		4 / 6 ASN A 102
ILE A 192
ASN A 134
ASN A 126
 CS4  A 233 ( 4.1A)
None
None
None
 1.20A 1h7xD-2oqzA:
undetectable		 1h7xD-2oqzA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2oqz SORTASE B
(Bacillus
anthracis) 		5 / 11 LEU A 177
VAL A 228
ASN A 126
ILE A  92
ILE A 136
 None
 1.16A 2uxoB-2oqzA:
undetectable		 2uxoB-2oqzA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 2oqz SORTASE B
(Bacillus
anthracis) 		3 / 3 HIS A 163
MET A 154
MET A  87
 None
 1.43A 2vj1A-2oqzA:
undetectable		 2vj1A-2oqzA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0S_A_PX9A201_0
(BETA-LACTOGLOBULIN)		 2oqz SORTASE B
(Bacillus
anthracis) 		5 / 12 LEU A 166
ILE A  85
VAL A 228
VAL A 246
LEU A 151
 None
 0.94A 4y0sA-2oqzA:
undetectable		 4y0sA-2oqzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2oqz SORTASE B
(Bacillus
anthracis) 		4 / 7 ILE A  52
VAL A 128
ILE A  96
PHE A 172
 None
 0.84A 5hieC-2oqzA:
undetectable		 5hieC-2oqzA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 2oqz SORTASE B
(Bacillus
anthracis) 		3 / 3 LYS A 249
VAL A 251
ASP A 225
 None
 0.70A 6fgdA-2oqzA:
undetectable		 6fgdA-2oqzA:
20.71