SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2or2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 2or2 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Bacillus
thuringiensis) 		3 / 3 ALA A  63
THR A  31
PHE A 101
 None
 0.60A 2c6nB-2or2A:
undetectable		 2c6nB-2or2A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 2or2 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Bacillus
thuringiensis) 		5 / 12 ARG A  69
HIS A  32
ASP A  67
ASP A 198
GLU A 117
 None
 1.30A 3lmyA-2or2A:
5.2		 3lmyA-2or2A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_B_CP6B563_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 2or2 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Bacillus
thuringiensis) 		5 / 12 ARG A  69
HIS A  32
ASP A  67
ASP A 198
GLU A 117
 None
 1.31A 3lmyB-2or2A:
5.8		 3lmyB-2or2A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NCQ_A_ACTA121_0
(NITROGEN REGULATORY
PROTEIN P-II
(GLNB-2))		 2or2 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Bacillus
thuringiensis) 		4 / 4 MET A 215
LYS A 212
ASP A 216
ASP A 259
 None
 1.48A 3ncqA-2or2A:
0.2		 3ncqA-2or2A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 2or2 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Bacillus
thuringiensis) 		3 / 3 TYR A  57
TYR A 285
GLU A  52
 None
 0.94A 3pfgA-2or2A:
undetectable		 3pfgA-2or2A:
20.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 2or2 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Bacillus
thuringiensis) 		3 / 3 LYS A 115
ARG A 163
TRP A 178
 None
 0.69A 4i90A-2or2A:
42.9		 4i90A-2or2A:
41.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 2or2 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Bacillus
thuringiensis) 		3 / 3 ARG A 163
HIS A  32
ARG A  69
 None
 0.75A 5iaoC-2or2A:
undetectable		 5iaoC-2or2A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 2or2 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Bacillus
thuringiensis) 		3 / 3 ARG A 163
HIS A  32
ARG A  69
 None
 0.77A 5iaoF-2or2A:
undetectable		 5iaoF-2or2A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2or2 1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE
(Bacillus
thuringiensis) 		4 / 8 PHE A  55
ARG A  69
ILE A  68
GLY A  70
 None
 0.99A 5nzxA-2or2A:
undetectable		 5nzxA-2or2A:
24.60