SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2orz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 2orz NEUROPILIN-1
(Rattus
norvegicus) 		4 / 7 TYR A 565
ASN A 451
TRP A 484
GLY A 453
 None
 1.36A 1mxgA-2orzA:
undetectable		 1mxgA-2orzA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 2orz NEUROPILIN-1
(Rattus
norvegicus) 		4 / 4 LEU A 464
PRO A 398
ILE A 426
LEU A 333
 None
 1.12A 1ya4C-2orzA:
undetectable		 1ya4C-2orzA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 2orz NEUROPILIN-1
(Rattus
norvegicus) 		4 / 8 TYR A 480
GLU A 483
SER A 450
VAL A 510
 None
 1.12A 3b9lA-2orzA:
undetectable		 3b9lA-2orzA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 2orz NEUROPILIN-1
(Rattus
norvegicus) 		3 / 3 PRO A 566
PHE A 540
LYS A 514
 None
 1.13A 3bjwG-2orzA:
undetectable		 3bjwG-2orzA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 2orz NEUROPILIN-1
(Rattus
norvegicus) 		4 / 8 ASN A 451
ALA A 449
SER A 450
LEU A 473
 None
 1.14A 4ijiF-2orzA:
undetectable		 4ijiF-2orzA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 2orz NEUROPILIN-1
(Rattus
norvegicus) 		5 / 12 GLY A 366
VAL A 465
LEU A 333
ASN A 545
ILE A 362
 None
 1.14A 4pd5A-2orzA:
undetectable		 4pd5A-2orzA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 2orz NEUROPILIN-1
(Rattus
norvegicus) 		5 / 12 GLY A 366
VAL A 465
LEU A 333
ASN A 545
ILE A 362
 None
 1.10A 4pd9A-2orzA:
undetectable		 4pd9A-2orzA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_C_Y70C151_1
(CEREBLON ISOFORM 4)		 2orz NEUROPILIN-1
(Rattus
norvegicus) 		4 / 8 PHE A 561
TRP A 526
TRP A 484
TYR A 565
 None
 1.10A 4v2zC-2orzA:
undetectable		 4v2zC-2orzA:
18.79