SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ose'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_B_ESTB354_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		4 / 8 VAL A  17
TYR A 174
PRO A  15
VAL A 169
 None
 0.99A 1fduB-2oseA:
undetectable		 1fduB-2oseA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		4 / 5 GLY A 127
GLN A 172
VAL A 169
SER A 125
 None
 1.20A 1p6kB-2oseA:
undetectable		 1p6kB-2oseA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		4 / 5 GLY A 127
GLN A 172
VAL A 169
SER A 125
 None
 1.16A 1rs6B-2oseA:
undetectable		 1rs6B-2oseA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		5 / 7 ILE A  33
LEU A  35
TYR A  76
THR A 146
LEU A 131
 None
 1.43A 1v55A-2oseA:
undetectable
1v55J-2oseA:
undetectable		 1v55A-2oseA:
17.28
1v55J-2oseA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		5 / 8 ILE A  33
LEU A  35
TYR A  76
THR A 146
LEU A 131
 None
 1.42A 1v55N-2oseA:
undetectable
1v55W-2oseA:
undetectable		 1v55N-2oseA:
17.28
1v55W-2oseA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		4 / 5 GLY A 127
GLN A 172
VAL A 169
SER A 125
 None
 1.32A 1zzqB-2oseA:
undetectable		 1zzqB-2oseA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		4 / 5 GLY A 127
GLN A 172
VAL A 169
SER A 125
 None
 1.35A 1zzuA-2oseA:
undetectable		 1zzuA-2oseA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		4 / 5 GLY A 127
GLN A 172
VAL A 169
SER A 125
 None
 1.17A 1zzuB-2oseA:
undetectable		 1zzuB-2oseA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		5 / 7 ILE A  33
LEU A  35
TYR A  76
THR A 146
LEU A 131
 None
 1.41A 3ag3A-2oseA:
undetectable
3ag3J-2oseA:
undetectable		 3ag3A-2oseA:
17.28
3ag3J-2oseA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		3 / 3 ASP A  94
HIS A  82
LYS A  80
 None
 0.96A 4qzuD-2oseA:
undetectable		 4qzuD-2oseA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		5 / 10 VAL A 168
PHE A  47
TYR A 107
ALA A  39
PHE A  40
 None
 1.13A 5mxbA-2oseA:
undetectable		 5mxbA-2oseA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		4 / 5 GLY A 127
GLN A 172
VAL A 169
SER A 125
 None
 1.15A 5vunA-2oseA:
undetectable		 5vunA-2oseA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_B_LEVB801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		3 / 3 TYR A 121
LEU A 128
ASP A 153
 None
 0.82A 5zv2B-2oseA:
undetectable		 5zv2B-2oseA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		4 / 5 ASN A  24
VAL A 179
LEU A  31
SER A 199
 None
 1.19A 6a7pA-2oseA:
undetectable		 6a7pA-2oseA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 2ose PROBABLE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
(Mimivirus) 		5 / 12 TYR A 107
LEU A   8
ILE A 112
PHE A 116
VAL A 168
 None
 1.17A 6djzB-2oseA:
undetectable		 6djzB-2oseA:
21.21