SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2osn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		4 / 8 LEU A   4
GLY A  30
HIS A  48
PHE A 101
 None
 0.73A 1sv9A-2osnA:
17.2		 1sv9A-2osnA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TD7_A_NFLA2001_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		6 / 9 LEU A   4
LYS A   8
ILE A  11
TRP A  19
GLY A  30
PHE A 101
 None
 0.75A 1td7A-2osnA:
19.5		 1td7A-2osnA:
61.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TH6_A_OINA401_1
(PHOSPHOLIPASE A2)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
 0.98A 1th6A-2osnA:
17.1		 1th6A-2osnA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ARM_A_OINA401_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		5 / 7 GLY A  30
HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
 0.99A 2armA-2osnA:
17.1		 2armA-2osnA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		6 / 11 ILE A  11
TYR A  25
GLY A  30
LEU A  41
PHE A 101
TYR A 106
 None
 0.56A 2azyA-2osnA:
16.8		 2azyA-2osnA:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2B17_A_DIFA701_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		5 / 10 LEU A   4
GLY A  30
HIS A  48
ASP A  49
PHE A 101
 None
 0.88A 2b17A-2osnA:
17.2		 2b17A-2osnA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DPZ_A_TYLA2001_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		4 / 6 LEU A   4
HIS A  48
ASP A  49
TYR A  52
 None
 0.92A 2dpzA-2osnA:
17.3		 2dpzA-2osnA:
36.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		4 / 8 LYS A   3
HIS A  48
ASP A  94
ALA A  55
 None
 1.29A 2rk8A-2osnA:
2.0		 2rk8A-2osnA:
10.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FO7_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
 0.99A 3fo7A-2osnA:
17.1		 3fo7A-2osnA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H1X_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		4 / 5 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
 0.94A 3h1xA-2osnA:
17.2		 3h1xA-2osnA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OSH_A_OINA5811_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		6 / 9 LEU A   4
PHE A   7
ILE A  11
TRP A  19
GLY A  30
HIS A  48
 None
 0.70A 3oshA-2osnA:
19.7		 3oshA-2osnA:
62.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		4 / 5 TYR A  70
ILE A  77
LEU A   4
PHE A   7
 None
 0.90A 5kmdC-2osnA:
undetectable
5kmdD-2osnA:
undetectable		 5kmdC-2osnA:
16.41
5kmdD-2osnA:
16.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6CE2_B_SVRB202_2
(-)		 2osn PHOSPHOLIPASE A2
ISOFORM 3
(Bungarus
caeruleus) 		5 / 12 GLY A  30
GLY A  32
TYR A  52
ASN A  62
PRO A  63
 None
CL  A 121 ( 4.4A)
None
None
None
 0.96A 6ce2B-2osnA:
16.6		 6ce2B-2osnA:
33.60