SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ot9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 LEU A 104
ILE A 121
ASP A  88
PRO A  87
 None
None
None
SRT  A 201 ( 4.0A)
 1.11A 1ditH-2ot9A:
undetectable
1ditP-2ot9A:
undetectable		 1ditH-2ot9A:
21.32
1ditP-2ot9A:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.24A 1zzrA-2ot9A:
undetectable
1zzrB-2ot9A:
undetectable		 1zzrA-2ot9A:
19.07
1zzrB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.24A 1zzrA-2ot9A:
undetectable
1zzrB-2ot9A:
undetectable		 1zzrA-2ot9A:
19.07
1zzrB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.25A 1zzuA-2ot9A:
undetectable
1zzuB-2ot9A:
undetectable		 1zzuA-2ot9A:
19.07
1zzuB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.25A 1zzuA-2ot9A:
undetectable
1zzuB-2ot9A:
undetectable		 1zzuA-2ot9A:
19.07
1zzuB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 ARG A 101
ASN A 123
THR A 176
 None
 0.87A 2q63A-2ot9A:
undetectable		 2q63A-2ot9A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 8 LEU A 137
ALA A 141
MET A 144
MET A  40
LEU A  44
 None
None
NA  A 181 (-4.4A)
NA  A 181 (-3.1A)
None
 1.33A 2yfxA-2ot9A:
undetectable		 2yfxA-2ot9A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.25A 3dqrA-2ot9A:
undetectable
3dqrB-2ot9A:
undetectable		 3dqrA-2ot9A:
19.07
3dqrB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.24A 3jx2A-2ot9A:
undetectable
3jx2B-2ot9A:
undetectable		 3jx2A-2ot9A:
19.07
3jx2B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.25A 3jx2A-2ot9A:
undetectable
3jx2B-2ot9A:
undetectable		 3jx2A-2ot9A:
19.07
3jx2B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.24A 3jx3A-2ot9A:
undetectable
3jx3B-2ot9A:
undetectable		 3jx3A-2ot9A:
19.07
3jx3B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.24A 3jx3A-2ot9A:
undetectable
3jx3B-2ot9A:
undetectable		 3jx3A-2ot9A:
19.07
3jx3B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.20A 3jx4A-2ot9A:
undetectable
3jx4B-2ot9A:
undetectable		 3jx4A-2ot9A:
19.07
3jx4B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.27A 3jx4A-2ot9A:
undetectable
3jx4B-2ot9A:
undetectable		 3jx4A-2ot9A:
19.07
3jx4B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.20A 3jx5A-2ot9A:
undetectable
3jx5B-2ot9A:
undetectable		 3jx5A-2ot9A:
19.07
3jx5B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.25A 3jx5A-2ot9A:
undetectable
3jx5B-2ot9A:
undetectable		 3jx5A-2ot9A:
19.07
3jx5B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.27A 3jx6A-2ot9A:
undetectable
3jx6B-2ot9A:
undetectable		 3jx6A-2ot9A:
19.07
3jx6B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.26A 3nljA-2ot9A:
undetectable
3nljB-2ot9A:
undetectable		 3nljA-2ot9A:
19.07
3nljB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.27A 3nljA-2ot9A:
undetectable
3nljB-2ot9A:
undetectable		 3nljA-2ot9A:
19.07
3nljB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.22A 3nlpA-2ot9A:
undetectable
3nlpB-2ot9A:
undetectable		 3nlpA-2ot9A:
19.07
3nlpB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.25A 3nlpA-2ot9A:
undetectable
3nlpB-2ot9A:
undetectable		 3nlpA-2ot9A:
19.07
3nlpB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.24A 3nlqA-2ot9A:
undetectable
3nlqB-2ot9A:
undetectable		 3nlqA-2ot9A:
19.07
3nlqB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.19A 3nlrA-2ot9A:
undetectable
3nlrB-2ot9A:
undetectable		 3nlrA-2ot9A:
19.07
3nlrB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ALA A 130
VAL A 170
VAL A 132
LEU A 105
 None
 0.80A 3o14A-2ot9A:
undetectable		 3o14A-2ot9A:
24.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.24A 4cx3A-2ot9A:
undetectable
4cx3B-2ot9A:
undetectable		 4cx3A-2ot9A:
19.07
4cx3B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.23A 4cx3A-2ot9A:
undetectable
4cx3B-2ot9A:
undetectable		 4cx3A-2ot9A:
19.07
4cx3B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.23A 4cx4A-2ot9A:
undetectable
4cx4B-2ot9A:
undetectable		 4cx4A-2ot9A:
19.07
4cx4B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.24A 4cx4A-2ot9A:
undetectable
4cx4B-2ot9A:
undetectable		 4cx4A-2ot9A:
19.07
4cx4B-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.21A 5addA-2ot9A:
undetectable
5addB-2ot9A:
undetectable		 5addA-2ot9A:
19.07
5addB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.22A 5addA-2ot9A:
undetectable
5addB-2ot9A:
undetectable		 5addA-2ot9A:
19.07
5addB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.21A 5adeA-2ot9A:
undetectable
5adeB-2ot9A:
undetectable		 5adeA-2ot9A:
19.07
5adeB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.23A 5adeA-2ot9A:
undetectable
5adeB-2ot9A:
undetectable		 5adeA-2ot9A:
19.07
5adeB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 152
ARG A 179
VAL A 170
PHE A  49
 None
 1.23A 5g0pA-2ot9A:
undetectable
5g0pB-2ot9A:
undetectable		 5g0pA-2ot9A:
19.07
5g0pB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 PHE A  49
VAL A 152
ARG A 179
VAL A 170
 None
 1.25A 5g0pA-2ot9A:
undetectable
5g0pB-2ot9A:
undetectable		 5g0pA-2ot9A:
19.07
5g0pB-2ot9A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 VAL A 132
HIS A 168
VAL A 161
 None
 0.71A 5jmnC-2ot9A:
undetectable		 5jmnC-2ot9A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 LEU A 105
VAL A 132
LEU A 137
VAL A 170
 None
 0.95A 5x7zA-2ot9A:
undetectable		 5x7zA-2ot9A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2ot9 HYPOTHETICAL PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 ILE A 148
LEU A 140
TYR A 107
LEU A  44
LEU A  45
 None
 0.91A 6f6nA-2ot9A:
0.2
6f6nB-2ot9A:
undetectable		 6f6nA-2ot9A:
18.33
6f6nB-2ot9A:
15.56