SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2otn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 PHE A 194
ALA A 169
PHE A 159
PHE A 150
None
1.23A 1lquA-2otnA:
undetectable
1lquA-2otnA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A 214
GLN A 178
ASN A 212
ASP A 175
None
1.14A 1p6kA-2otnA:
undetectable
1p6kA-2otnA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A 214
GLN A 178
ASN A 212
ASP A 175
None
1.17A 1rs7B-2otnA:
undetectable
1rs7B-2otnA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.70A 1v54C-2otnA:
undetectable
1v54J-2otnA:
undetectable
1v54C-2otnA:
21.78
1v54J-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.74A 1v54P-2otnA:
undetectable
1v54W-2otnA:
undetectable
1v54P-2otnA:
21.78
1v54W-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.70A 1v55C-2otnA:
undetectable
1v55J-2otnA:
undetectable
1v55C-2otnA:
21.78
1v55J-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.72A 1v55P-2otnA:
undetectable
1v55W-2otnA:
undetectable
1v55P-2otnA:
21.78
1v55W-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOH_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 5 LEU A 258
GLY A 126
ALA A 230
ILE A 260
None
0.67A 2aohB-2otnA:
undetectable
2aohB-2otnA:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
3 / 3 THR A 182
PRO A 180
PRO A 186
None
0.75A 2d55C-2otnA:
undetectable
2d55C-2otnA:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.68A 2dyrC-2otnA:
undetectable
2dyrJ-2otnA:
undetectable
2dyrC-2otnA:
21.78
2dyrJ-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.72A 2dyrP-2otnA:
undetectable
2dyrW-2otnA:
undetectable
2dyrP-2otnA:
21.78
2dyrW-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.75A 2dysC-2otnA:
undetectable
2dysJ-2otnA:
undetectable
2dysC-2otnA:
21.78
2dysJ-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.70A 2dysP-2otnA:
undetectable
2dysW-2otnA:
undetectable
2dysP-2otnA:
21.78
2dysW-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.72A 2eijC-2otnA:
undetectable
2eijJ-2otnA:
undetectable
2eijC-2otnA:
21.78
2eijJ-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.70A 2eijP-2otnA:
undetectable
2eijW-2otnA:
undetectable
2eijP-2otnA:
21.78
2eijW-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.73A 2eikP-2otnA:
undetectable
2eikW-2otnA:
undetectable
2eikP-2otnA:
21.78
2eikW-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.72A 2eilC-2otnA:
undetectable
2eilJ-2otnA:
undetectable
2eilC-2otnA:
21.78
2eilJ-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.76A 2eilP-2otnA:
undetectable
2eilW-2otnA:
undetectable
2eilP-2otnA:
21.78
2eilW-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.73A 2eimC-2otnA:
undetectable
2eimJ-2otnA:
undetectable
2eimC-2otnA:
21.78
2eimJ-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.68A 2eimP-2otnA:
undetectable
2eimW-2otnA:
undetectable
2eimP-2otnA:
21.78
2eimW-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.80A 2einC-2otnA:
undetectable
2einJ-2otnA:
undetectable
2einC-2otnA:
21.78
2einJ-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.69A 2zxwC-2otnA:
undetectable
2zxwJ-2otnA:
undetectable
2zxwC-2otnA:
21.78
2zxwJ-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.72A 3asnP-2otnA:
undetectable
3asnW-2otnA:
undetectable
3asnP-2otnA:
21.78
3asnW-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.65A 3asoC-2otnA:
undetectable
3asoJ-2otnA:
undetectable
3asoC-2otnA:
21.78
3asoJ-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.69A 3asoP-2otnA:
undetectable
3asoW-2otnA:
undetectable
3asoP-2otnA:
21.78
3asoW-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A 214
GLN A 178
ASN A 212
ASP A 175
None
1.31A 3n62A-2otnA:
undetectable
3n62A-2otnA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A 214
GLN A 178
ASN A 212
ASP A 175
None
1.28A 3n62B-2otnA:
undetectable
3n62B-2otnA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 8 ARG A 214
GLN A 178
ASN A 212
ASP A 175
None
1.32A 3n66B-2otnA:
undetectable
3n66B-2otnA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
3 / 3 ASN A 149
ALA A 158
ARG A 147
None
0.89A 3tj7C-2otnA:
undetectable
3tj7D-2otnA:
undetectable
3tj7C-2otnA:
20.95
3tj7D-2otnA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.72A 5b3sP-2otnA:
undetectable
5b3sP-2otnA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 6 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.70A 5w97C-2otnA:
undetectable
5w97J-2otnA:
undetectable
5w97C-2otnA:
21.78
5w97J-2otnA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 6 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.69A 5x19P-2otnA:
undetectable
5x19P-2otnA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
2otn DIAMINOPIMELATE
EPIMERASE

(Bacillus
anthracis)
4 / 7 ARG A  81
LYS A 271
LEU A 258
LEU A  12
None
0.72A 5x1fP-2otnA:
undetectable
5x1fW-2otnA:
undetectable
5x1fP-2otnA:
21.78
5x1fW-2otnA:
14.93