SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2otp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_A_PAUA6001_0
(PANTOTHENATE KINASE)		 2otp LEUKOCYTE
IMMUNOGLOBULIN-LIKE
RECEPTOR SUBFAMILY A
MEMBER 2
(Homo
sapiens) 		5 / 9 LYS A  55
GLY A  54
LEU A  30
TYR A  35
ILE A  50
 None
 1.37A 1sq5A-2otpA:
undetectable		 1sq5A-2otpA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_B_PAUB6003_0
(PANTOTHENATE KINASE)		 2otp LEUKOCYTE
IMMUNOGLOBULIN-LIKE
RECEPTOR SUBFAMILY A
MEMBER 2
(Homo
sapiens) 		5 / 10 LYS A  55
GLY A  54
LEU A  30
TYR A  35
ILE A  50
 None
 1.37A 1sq5B-2otpA:
undetectable		 1sq5B-2otpA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_C_PAUC6002_0
(PANTOTHENATE KINASE)		 2otp LEUKOCYTE
IMMUNOGLOBULIN-LIKE
RECEPTOR SUBFAMILY A
MEMBER 2
(Homo
sapiens) 		5 / 9 LYS A  55
GLY A  54
LEU A  30
TYR A  35
ILE A  50
 None
 1.37A 1sq5C-2otpA:
undetectable		 1sq5C-2otpA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 2otp LEUKOCYTE
IMMUNOGLOBULIN-LIKE
RECEPTOR SUBFAMILY A
MEMBER 2
(Homo
sapiens) 		5 / 10 LYS A  55
GLY A  54
LEU A  30
TYR A  35
ILE A  50
 None
 1.37A 1sq5D-2otpA:
undetectable		 1sq5D-2otpA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 2otp LEUKOCYTE
IMMUNOGLOBULIN-LIKE
RECEPTOR SUBFAMILY A
MEMBER 2
(Homo
sapiens) 		4 / 5 GLU A  90
GLY A 160
SER A  14
GLY A  13
 None
 1.11A 5kprA-2otpA:
undetectable		 5kprA-2otpA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 2otp LEUKOCYTE
IMMUNOGLOBULIN-LIKE
RECEPTOR SUBFAMILY A
MEMBER 2
(Homo
sapiens) 		3 / 3 GLU A  84
ASP A  87
PRO A  88
 None
 0.65A 6berA-2otpA:
undetectable		 6berA-2otpA:
5.29