SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ott'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 2ott T-CELL SURFACE
GLYCOPROTEIN CD5
(Homo
sapiens) 		4 / 6 LEU X  82
VAL X  26
VAL X  98
ASP X  37
 None
 1.13A 3fwgA-2ottX:
undetectable		 3fwgA-2ottX:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 2ott T-CELL SURFACE
GLYCOPROTEIN CD5
(Homo
sapiens) 		4 / 7 SER X  11
VAL X   9
VAL X  26
LEU X  35
 None
 0.88A 3o14A-2ottX:
undetectable		 3o14A-2ottX:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2ott T-CELL SURFACE
GLYCOPROTEIN CD5
(Homo
sapiens) 		4 / 6 LEU X  82
VAL X  26
VAL X  98
ASP X  37
 None
 1.14A 3wrhE-2ottX:
undetectable		 3wrhE-2ottX:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 2ott T-CELL SURFACE
GLYCOPROTEIN CD5
(Homo
sapiens) 		4 / 6 LEU X  82
VAL X  26
VAL X  98
ASP X  37
 None
 1.14A 3wrjE-2ottX:
undetectable		 3wrjE-2ottX:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2ott T-CELL SURFACE
GLYCOPROTEIN CD5
(Homo
sapiens) 		4 / 6 LEU X  82
VAL X  26
VAL X  98
ASP X  37
 None
 1.11A 4ek1A-2ottX:
undetectable		 4ek1A-2ottX:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2ott T-CELL SURFACE
GLYCOPROTEIN CD5
(Homo
sapiens) 		4 / 8 LYS X  97
THR X  23
LEU X  75
VAL X  14
 None
 0.92A 4iizB-2ottX:
undetectable		 4iizB-2ottX:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 2ott T-CELL SURFACE
GLYCOPROTEIN CD5
(Homo
sapiens) 		4 / 6 LEU X  82
VAL X  26
VAL X  98
ASP X  37
 None
 1.17A 4kkyX-2ottX:
undetectable		 4kkyX-2ottX:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_0
(SERUM ALBUMIN)		 2ott T-CELL SURFACE
GLYCOPROTEIN CD5
(Homo
sapiens) 		5 / 12 VAL X   9
VAL X  24
VAL X  64
ALA X  67
ARG X  91
 None
 1.44A 6a7pB-2ottX:
undetectable		 6a7pB-2ottX:
10.67