SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2otu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 2otu FV HEAVY CHAIN
VARIABLE DOMAIN
(Mus
musculus) 		3 / 3 TYR B  35
LEU B  18
LYS B  19
 None
 0.78A 3sueD-2otuB:
undetectable		 3sueD-2otuB:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2otu FV HEAVY CHAIN
VARIABLE DOMAIN
(Mus
musculus) 		4 / 7 ALA B  92
THR B  91
VAL B 114
GLU B  89
 None
 0.84A 5ecoD-2otuB:
undetectable		 5ecoD-2otuB:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2otu FV HEAVY CHAIN
VARIABLE DOMAIN
(Mus
musculus) 		4 / 8 ALA B  92
LEU B  86
LEU B  20
LEU B  18
 None
 0.71A 5jqbA-2otuB:
undetectable
5jqbB-2otuB:
undetectable		 5jqbA-2otuB:
17.53
5jqbB-2otuB:
21.84