SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oua'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 7 GLY A 216
ASP A 102
HIS A  57
ALA A  55
 AES  A9001 (-4.9A)
None
None
None
 0.99A 1gxsA-2ouaA:
undetectable
1gxsB-2ouaA:
undetectable		 1gxsA-2ouaA:
23.74
1gxsB-2ouaA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		6 / 12 GLY A  19
GLY A  44
ILE A  17
TYR A 120
PHE A 199
SER A 139
 None
 1.41A 1ri4A-2ouaA:
undetectable		 1ri4A-2ouaA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 8 ASP A 102
PHE A  94
SER A 195
ALA A 104
 None
None
AES  A9001 (-2.5A)
None
 0.95A 1rqpC-2ouaA:
undetectable		 1rqpC-2ouaA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 8 ASP A 102
PHE A  94
SER A 195
ALA A 104
 None
None
AES  A9001 (-2.5A)
None
 0.95A 1rqpA-2ouaA:
undetectable		 1rqpA-2ouaA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 8 ASP A 102
PHE A  94
SER A 195
ALA A 104
 None
None
AES  A9001 (-2.5A)
None
 0.95A 2v7uA-2ouaA:
undetectable		 2v7uA-2ouaA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		3 / 3 SER A 184
ARG A 182
GLN A 163
 None
 0.80A 2xnrA-2ouaA:
undetectable		 2xnrA-2ouaA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		3 / 3 GLY A 197
GLY A  18
GLY A  44
 None
 0.44A 3bogC-2ouaA:
undetectable		 3bogC-2ouaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 5 SER A 198
SER A 120
VAL A 120
GLY A  44
 None
 0.97A 3rxhA-2ouaA:
9.4		 3rxhA-2ouaA:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 7 THR A 183
GLY A 160
GLY A 223
THR A 222
 None
 0.83A 3tajA-2ouaA:
undetectable		 3tajA-2ouaA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 5 SER A 110
ILE A  16
GLY A 108
PRO A  50
 None
 0.83A 3uboB-2ouaA:
undetectable		 3uboB-2ouaA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 8 ASP A  15
ILE A  16
VAL A 106
GLY A 108
 None
 0.63A 4ac9C-2ouaA:
2.7		 4ac9C-2ouaA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 8 ASP A  15
ILE A  16
VAL A 106
GLY A 108
 None
 0.61A 4acaC-2ouaA:
3.0		 4acaC-2ouaA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 8 ASP A  15
ILE A  16
VAL A 106
GLY A 108
 None
 0.61A 4acbC-2ouaA:
2.7		 4acbC-2ouaA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		5 / 12 GLY A 196
GLY A  84
VAL A  64
GLY A  18
GLY A  19
 None
 0.95A 5koxA-2ouaA:
undetectable		 5koxA-2ouaA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		3 / 3 GLY A  56
VAL A  64
MET A  37
 None
 0.65A 5ycpA-2ouaA:
undetectable		 5ycpA-2ouaA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 5 ALA A  34
SER A  43
GLY A 140
TYR A 120
 None
 1.25A 5yodB-2ouaA:
10.1		 5yodB-2ouaA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 5 ALA A  34
SER A  43
GLY A 140
TYR A 120
 None
 1.15A 5yodD-2ouaA:
6.1		 5yodD-2ouaA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2oua SERINE PROTEASE
(Nocardiopsis
alba) 		4 / 7 ILE A  17
VAL A  44
ILE A  66
THR A  36
 None
 1.01A 6cduF-2ouaA:
undetectable
6cduG-2ouaA:
undetectable		 6cduF-2ouaA:
21.21
6cduG-2ouaA:
21.21