SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oud'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		5 / 12 ILE A 325
GLY A 332
GLY A 411
LEU A 405
LEU A 322
 None
 1.03A 1rjdA-2oudA:
undetectable		 1rjdA-2oudA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		5 / 12 ILE A 325
GLY A 332
GLY A 411
LEU A 405
LEU A 322
 None
 1.01A 1rjdB-2oudA:
undetectable		 1rjdB-2oudA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		5 / 12 ILE A 325
GLY A 332
GLY A 411
LEU A 405
LEU A 322
 None
 1.03A 1rjdC-2oudA:
undetectable		 1rjdC-2oudA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		4 / 6 THR A 467
PHE A 458
PHE A 391
HIS A 426
 None
 1.33A 1tt0A-2oudA:
undetectable		 1tt0A-2oudA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		4 / 6 THR A 467
PHE A 458
PHE A 391
HIS A 426
 None
 1.33A 1tt0B-2oudA:
0.0		 1tt0B-2oudA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		4 / 6 THR A 467
PHE A 458
PHE A 391
HIS A 426
 None
 1.35A 1tt0C-2oudA:
0.0		 1tt0C-2oudA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		4 / 6 THR A 467
PHE A 458
PHE A 391
HIS A 426
 None
 1.32A 1tt0D-2oudA:
0.0		 1tt0D-2oudA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		5 / 12 GLY A 411
GLY A 332
GLN A 381
ASP A 377
SER A 413
 None
None
None
CL  A   1 ( 4.9A)
None
 1.08A 1wg8A-2oudA:
undetectable		 1wg8A-2oudA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		3 / 3 GLU A 318
GLN A 409
ARG A 414
 None
None
CL  A   1 ( 4.1A)
 0.87A 2w3bB-2oudA:
undetectable		 2w3bB-2oudA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O01_B_DXCB1_0
(CELL INVASION
PROTEIN SIPD)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		5 / 9 ARG A 442
ILE A 325
LYS A 441
ALA A 416
LEU A 423
 None
 1.45A 3o01A-2oudA:
0.0
3o01B-2oudA:
undetectable		 3o01A-2oudA:
19.43
3o01B-2oudA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		3 / 3 LYS A 425
ARG A 384
LYS A 371
 None
 1.45A 3okxA-2oudA:
undetectable		 3okxA-2oudA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLA_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		4 / 8 LEU A 404
LEU A 475
LYS A 371
ILE A 352
 None
 0.75A 4klaA-2oudA:
undetectable		 4klaA-2oudA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		4 / 5 ILE A 444
PRO A 443
HIS A 491
VAL A 419
 None
 1.32A 4s0vA-2oudA:
undetectable		 4s0vA-2oudA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJD_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		5 / 9 LEU A 331
LEU A 423
ILE A 445
GLN A 454
LEU A 383
 None
 1.50A 5ljdA-2oudA:
undetectable		 5ljdA-2oudA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		5 / 9 LEU A 455
PRO A 447
GLY A 453
LEU A 383
GLN A 381
 None
 1.49A 5o96E-2oudA:
undetectable
5o96F-2oudA:
undetectable		 5o96E-2oudA:
19.84
5o96F-2oudA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 2oud DUAL SPECIFICITY
PROTEIN PHOSPHATASE
10
(Homo
sapiens) 		5 / 12 LEU A 462
ILE A 470
ALA A 434
LEU A 475
MET A 476
 None
 1.24A 6ie8A-2oudA:
undetectable		 6ie8A-2oudA:
20.30