SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ov1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 2ov1 PERIPLASMIC BINDING
PROTEIN COMPONENT OF
AN ABC TYPE ZINC
UPTAKE TRANSPORTER
(Synechocystis
sp.
PCC
6803) 		4 / 5 TYR A  85
PRO A 111
LEU A 113
THR A  52
 None
 1.32A 1i2wA-2ov1A:
undetectable		 1i2wA-2ov1A:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 2ov1 PERIPLASMIC BINDING
PROTEIN COMPONENT OF
AN ABC TYPE ZINC
UPTAKE TRANSPORTER
(Synechocystis
sp.
PCC
6803) 		4 / 8 ILE A 301
ILE A 305
ILE A 260
ASN A 282
 None
 0.53A 2nniA-2ov1A:
undetectable		 2nniA-2ov1A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 2ov1 PERIPLASMIC BINDING
PROTEIN COMPONENT OF
AN ABC TYPE ZINC
UPTAKE TRANSPORTER
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A  63
VAL A  53
GLY A  66
LEU A 198
 None
 1.00A 5sxqA-2ov1A:
undetectable		 5sxqA-2ov1A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 2ov1 PERIPLASMIC BINDING
PROTEIN COMPONENT OF
AN ABC TYPE ZINC
UPTAKE TRANSPORTER
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A  63
VAL A  53
GLY A  66
LEU A 198
 None
 0.99A 5sxtA-2ov1A:
undetectable		 5sxtA-2ov1A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 2ov1 PERIPLASMIC BINDING
PROTEIN COMPONENT OF
AN ABC TYPE ZINC
UPTAKE TRANSPORTER
(Synechocystis
sp.
PCC
6803) 		4 / 8 GLU A  63
VAL A  53
GLY A  66
LEU A 198
 None
 0.98A 5sxtB-2ov1A:
undetectable		 5sxtB-2ov1A:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 2ov1 PERIPLASMIC BINDING
PROTEIN COMPONENT OF
AN ABC TYPE ZINC
UPTAKE TRANSPORTER
(Synechocystis
sp.
PCC
6803) 		4 / 6 GLU A 197
GLU A  99
ALA A 100
LYS A 124
 None
 1.20A 6an0A-2ov1A:
undetectable		 6an0A-2ov1A:
21.08