SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ov9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
3 / 3 PRO A 101
THR A  92
PRO A  90
None
0.78A 2d55C-2ov9A:
undetectable
2d55C-2ov9A:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
5 / 12 PRO A 100
THR A 117
VAL A 116
LEU A 174
ILE A 192
None
1.46A 2xrlA-2ov9A:
undetectable
2xrlA-2ov9A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
5 / 12 GLY A 131
LEU A 136
LEU A 118
LEU A 172
VAL A 116
None
0.94A 2yqzB-2ov9A:
undetectable
2yqzB-2ov9A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
5 / 12 ILE A 192
GLY A 132
ALA A 135
VAL A 129
THR A 166
None
1.02A 3uq6B-2ov9A:
undetectable
3uq6B-2ov9A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
5 / 12 ILE A 192
GLY A 132
ALA A 135
VAL A 129
THR A 166
None
1.08A 3vaqB-2ov9A:
undetectable
3vaqB-2ov9A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
4 / 8 GLY A 132
TYR A 162
VAL A 129
TYR A 122
None
0.88A 4fgzA-2ov9A:
undetectable
4fgzA-2ov9A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
4 / 7 ARG A 113
THR A 175
ASP A 191
GLY A 197
None
0.95A 5hwaA-2ov9A:
undetectable
5hwaA-2ov9A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
3 / 3 VAL A 102
ARG A 164
PRO A 167
None
0.84A 5koxA-2ov9A:
undetectable
5koxA-2ov9A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
4 / 5 PRO A  94
GLY A  93
THR A  92
ASN A  96
None
0.95A 5x23A-2ov9A:
undetectable
5x23A-2ov9A:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
4 / 6 PRO A  94
GLY A  93
THR A  92
ASN A  96
None
1.01A 5x24A-2ov9A:
undetectable
5x24A-2ov9A:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
4 / 6 PRO A  94
GLY A  93
THR A  92
ASN A  96
None
1.12A 5xxiA-2ov9A:
undetectable
5xxiA-2ov9A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
3 / 3 MET A 179
ASP A 109
ARG A 193
None
1.18A 5z6jA-2ov9A:
undetectable
5z6jA-2ov9A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)
2ov9 HYPOTHETICAL PROTEIN
(Rhodococcus
jostii)
5 / 9 VAL A 116
GLY A 176
VAL A 112
ASP A 191
GLY A 190
None
1.37A 5zniA-2ov9A:
undetectable
5zniA-2ov9A:
16.35