SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ovi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BNN_B_FCNB1199_1 (EPOXIDASE)	2ovi	HYPOTHETICAL PROTEIN CHUX (Escherichia coli)	4 / 8	LEU A 137 HIS A 154 GLU A 111 ALA A 120	None	0.91A	2bnnA-2oviA: undetectable 2bnnB-2oviA: undetectable	2bnnA-2oviA: 24.15 2bnnB-2oviA: 24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QBL_A_CAMA517_0 (CYTOCHROME P450-CAM)	2ovi	HYPOTHETICAL PROTEIN CHUX (Escherichia coli)	4 / 7	PHE A 124 LEU A 156 VAL A 54 THR A 53	None	0.76A	2qblA-2oviA: undetectable	2qblA-2oviA: 16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N61_A_H4BA760_1 (NITRIC OXIDE SYNTHASE)	2ovi	HYPOTHETICAL PROTEIN CHUX (Escherichia coli)	4 / 6	VAL A 20 VAL A 32 PHE A 9 GLU A 23	None	1.46A	3n61A-2oviA: undetectable 3n61B-2oviA: undetectable	3n61A-2oviA: 18.75 3n61B-2oviA: 18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MFX_A_ACTA701_0 (GENOME POLYPROTEIN)	2ovi	HYPOTHETICAL PROTEIN CHUX (Escherichia coli)	4 / 5	THR A 66 HIS A 65 ALA A 67 ASP A 68	None	1.30A	5mfxA-2oviA: undetectable	5mfxA-2oviA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UTU_H_ADNH503_2 (ADENOSYLHOMOCYSTEINA SE)	2ovi	HYPOTHETICAL PROTEIN CHUX (Escherichia coli)	4 / 5	THR A 40 GLU A 111 THR A 119 LEU A 18	None	1.28A	5utuH-2oviA: undetectable	5utuH-2oviA: 16.84

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BNN_B_FCNB1199_1","EPOXIDASE;EPOXIDASE","2ovi","HYPOTHETICAL PROTEIN CHUX","Escherichia coli",4,"LEU A 137;HIS A 154;GLU A 111;ALA A 120","None","0.91A","2bnnA-2oviA:undetectable;2bnnB-2oviA:undetectable","2bnnA-2oviA:24.15;2bnnB-2oviA:24.15"],["2QBL_A_CAMA517_0","CYTOCHROME P450-CAM","2ovi","HYPOTHETICAL PROTEIN CHUX","Escherichia coli",4,"PHE A 124;LEU A 156;VAL A  54;THR A  53","None","0.76A","2qblA-2oviA:undetectable","2qblA-2oviA:16.39"],["3N61_A_H4BA760_1","NITRIC OXIDE SYNTHASE;NITRIC OXIDE SYNTHASE","2ovi","HYPOTHETICAL PROTEIN CHUX","Escherichia coli",4,"VAL A  20;VAL A  32;PHE A   9;GLU A  23","None","1.46A","3n61A-2oviA:undetectable;3n61B-2oviA:undetectable","3n61A-2oviA:18.75;3n61B-2oviA:18.75"],["5MFX_A_ACTA701_0","GENOME POLYPROTEIN","2ovi","HYPOTHETICAL PROTEIN CHUX","Escherichia coli",4,"THR A  66;HIS A  65;ALA A  67;ASP A  68","None","1.30A","5mfxA-2oviA:undetectable","5mfxA-2oviA:19.05"],["5UTU_H_ADNH503_2","ADENOSYLHOMOCYSTEINASE","2ovi","HYPOTHETICAL PROTEIN CHUX","Escherichia coli",4,"THR A  40;GLU A 111;THR A 119;LEU A  18","None","1.28A","5utuH-2oviA:undetectable","5utuH-2oviA:16.84"]]