SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ovl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 5 GLU A 223
ALA A 198
SER A  23
HIS A  25
 NA  A 400 (-3.6A)
None
None
None
 1.27A 1errA-2ovlA:
undetectable
1errB-2ovlA:
undetectable		 1errA-2ovlA:
21.29
1errB-2ovlA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		6 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
LEU A  16
 None
 1.41A 1jffB-2ovlA:
undetectable		 1jffB-2ovlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 ILE A 109
VAL A 273
ASP A 272
HIS A 326
TYR A  49
 None
 1.17A 1kiaB-2ovlA:
2.1		 1kiaB-2ovlA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 ILE A 109
VAL A 273
ASP A 272
HIS A 326
TYR A  49
 None
 1.19A 1nbhC-2ovlA:
undetectable		 1nbhC-2ovlA:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		6 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
LEU A  16
 None
 1.41A 2hxfB-2ovlA:
undetectable		 2hxfB-2ovlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		6 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
LEU A  16
 None
 1.41A 2hxhB-2ovlA:
undetectable		 2hxhB-2ovlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		6 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
LEU A  16
 None
 1.41A 2p4nB-2ovlA:
undetectable		 2p4nB-2ovlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		6 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
LEU A  16
 None
 1.41A 2wbeB-2ovlA:
undetectable		 2wbeB-2ovlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
ASP A 197
ASP A 272
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-2.7A)
None
 1.35A 2xinA-2ovlA:
6.1		 2xinA-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.26A 2xinA-2ovlA:
6.1		 2xinA-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_A_SORA397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.32A 2xinA-2ovlA:
6.1		 2xinA-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
ASP A 197
ASP A 272
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-2.7A)
None
 1.37A 2xinB-2ovlA:
6.1		 2xinB-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.24A 2xinB-2ovlA:
6.1		 2xinB-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_B_SORB397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.28A 2xinB-2ovlA:
6.1		 2xinB-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
ASP A 197
ASP A 272
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-2.7A)
None
 1.36A 2xinC-2ovlA:
5.5		 2xinC-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.25A 2xinC-2ovlA:
5.5		 2xinC-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_C_SORC397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.30A 2xinC-2ovlA:
5.5		 2xinC-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
ASP A 197
ASP A 272
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-2.7A)
None
 1.37A 2xinD-2ovlA:
4.9		 2xinD-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.21A 2xinD-2ovlA:
4.9		 2xinD-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XIN_D_SORD397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.28A 2xinD-2ovlA:
4.9		 2xinD-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 6 ARG A 180
ASP A 142
ILE A 141
TYR A 137
 None
 1.22A 2ya7C-2ovlA:
undetectable		 2ya7C-2ovlA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		6 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
LEU A  16
 None
 1.41A 3dcoB-2ovlA:
undetectable		 3dcoB-2ovlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 ALA A 210
ASN A 199
LEU A 214
ALA A 211
LEU A 143
 None
NA  A 400 (-3.8A)
None
None
None
 1.09A 3dzyA-2ovlA:
undetectable		 3dzyA-2ovlA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		6 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
LEU A  16
 None
 1.40A 3edlB-2ovlA:
undetectable		 3edlB-2ovlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 6 PRO A 271
LEU A 309
ALA A 286
PRO A 269
 None
 1.22A 3gv1A-2ovlA:
undetectable
3gv1C-2ovlA:
undetectable		 3gv1A-2ovlA:
18.55
3gv1C-2ovlA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		6 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
LEU A  16
 None
 1.40A 3iz0B-2ovlA:
undetectable		 3iz0B-2ovlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 5 HIS A 299
THR A 297
GLU A 224
ASP A 229
 None
None
NA  A 400 (-3.3A)
None
 1.42A 3tm4A-2ovlA:
undetectable		 3tm4A-2ovlA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 5 HIS A 299
THR A 297
GLU A 224
ASP A 229
 None
None
NA  A 400 (-3.3A)
None
 1.42A 3tm4B-2ovlA:
undetectable		 3tm4B-2ovlA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.25A 3ximB-2ovlA:
4.7		 3ximB-2ovlA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_B_SORB397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.31A 3ximB-2ovlA:
4.7		 3ximB-2ovlA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.17A 3ximD-2ovlA:
4.6		 3ximD-2ovlA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3XIM_D_SORD397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.28A 3ximD-2ovlA:
4.6		 3ximD-2ovlA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 8 ASP A 142
ILE A 141
GLY A 140
VAL A  53
 None
 0.80A 4acbB-2ovlA:
3.5
4acbC-2ovlA:
2.6		 4acbB-2ovlA:
22.02
4acbC-2ovlA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 8 ILE A  14
LEU A 325
ILE A  34
GLY A 300
 None
 0.68A 4hb8A-2ovlA:
undetectable		 4hb8A-2ovlA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.20A 4xiaB-2ovlA:
5.6		 4xiaB-2ovlA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIA_B_SORB400_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.27A 4xiaB-2ovlA:
5.6		 4xiaB-2ovlA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 ALA A 289
PHE A 282
THR A 281
THR A 305
LEU A 309
 None
 1.18A 4z7fC-2ovlA:
undetectable		 4z7fC-2ovlA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 4 LEU A 268
LEU A 266
GLY A 247
GLU A 223
 None
None
None
NA  A 400 (-3.6A)
 1.02A 5hhjA-2ovlA:
undetectable		 5hhjA-2ovlA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		6 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
LEU A  16
 None
 1.36A 5hnwB-2ovlA:
undetectable		 5hnwB-2ovlA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 VAL A 301
ASP A 303
HIS A 321
PHE A  31
LEU A  16
 None
 1.30A 5hnxB-2ovlA:
undetectable		 5hnxB-2ovlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		6 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
LEU A  16
 None
 1.32A 5hnyB-2ovlA:
undetectable		 5hnyB-2ovlA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNZ_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 VAL A 301
ASP A 303
LEU A  20
HIS A 321
PHE A  31
 None
 1.33A 5hnzB-2ovlA:
undetectable		 5hnzB-2ovlA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 ILE A 109
VAL A  36
ALA A  61
VAL A  64
GLY A  56
 None
 1.01A 5igjA-2ovlA:
undetectable		 5igjA-2ovlA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 ILE A 109
VAL A  36
ALA A  61
VAL A  64
GLY A  56
 None
 1.02A 5igtA-2ovlA:
undetectable		 5igtA-2ovlA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 5 LEU A 126
GLY A 116
ASP A 108
ILE A 109
 None
 0.93A 5ik1A-2ovlA:
undetectable		 5ik1A-2ovlA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 4 LEU A  33
ARG A  13
ILE A  14
PHE A  31
 None
 1.34A 5kirB-2ovlA:
0.4		 5kirB-2ovlA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 LEU A 111
ARG A  37
GLY A  46
GLY A  48
VAL A  36
 None
 1.32A 5o4yD-2ovlA:
undetectable
5o4yE-2ovlA:
undetectable		 5o4yD-2ovlA:
2.83
5o4yE-2ovlA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 5 ALA A 308
VAL A 273
PHE A 127
ILE A 109
 None
 1.05A 5of1B-2ovlA:
undetectable		 5of1B-2ovlA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 LEU A 114
ILE A 109
ILE A 117
GLY A 116
LEU A  47
 None
 0.97A 5twjA-2ovlA:
undetectable		 5twjA-2ovlA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 10 LEU A 114
ILE A 109
ILE A 117
GLY A 116
LEU A  47
 None
 1.03A 5twjB-2ovlA:
undetectable		 5twjB-2ovlA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.21A 5ximA-2ovlA:
6.1		 5ximA-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_A_SORA397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.34A 5ximA-2ovlA:
6.1		 5ximA-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.19A 5ximC-2ovlA:
6.1		 5ximC-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIM_C_SORC397_0
(D-XYLOSE ISOMERASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 HIS A  25
THR A  24
GLU A 224
GLU A 223
ASP A 197
 None
None
NA  A 400 (-3.3A)
NA  A 400 (-3.6A)
NA  A 400 (-2.7A)
 1.28A 5ximC-2ovlA:
6.1		 5ximC-2ovlA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_F_EVPF1301_1
()		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 4 GLY A 278
ASP A 108
ARG A 283
MET A 333
 None
 0.93A 5zrfA-2ovlA:
0.6		 5zrfA-2ovlA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		5 / 12 ALA A 235
PHE A 257
PHE A 282
ALA A 308
THR A 316
 None
 1.32A 6aycA-2ovlA:
undetectable		 6aycA-2ovlA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 2ovl PUTATIVE RACEMASE
(Streptomyces
coelicolor) 		4 / 9 VAL A 134
LEU A 123
VAL A 350
ASP A 303
 None
 0.88A 6c2mD-2ovlA:
undetectable		 6c2mD-2ovlA:
12.75