SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2owa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		4 / 6 GLY A 125
ILE A 123
GLN A 127
VAL A 107
 None
 0.97A 1rs7B-2owaA:
undetectable		 1rs7B-2owaA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		5 / 9 PHE A 104
ALA A 100
TYR A 103
GLY A 125
ILE A 131
 None
 0.95A 2v7bA-2owaA:
undetectable		 2v7bA-2owaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		5 / 9 PHE A 104
ALA A 100
TYR A 103
GLY A 125
ILE A 131
 None
 0.96A 2v7bB-2owaA:
undetectable		 2v7bB-2owaA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 LEU A 132
ARG A  99
GLY A  96
ALA A  55
 None
 0.94A 2xfsA-2owaA:
undetectable		 2xfsA-2owaA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		4 / 8 LEU A 132
ARG A  99
GLY A  96
ALA A  55
 None
 0.93A 2xh9A-2owaA:
undetectable		 2xh9A-2owaA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		5 / 10 PHE A  57
ALA A 100
VAL A  30
LEU A  50
PHE A  27
 None
 1.33A 3ay0A-2owaA:
undetectable		 3ay0A-2owaA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		5 / 12 ILE A  94
ALA A  55
LEU A  52
GLN A 130
VAL A  90
 None
 0.96A 3ix9A-2owaA:
undetectable		 3ix9A-2owaA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 ASP A  20
LYS A  21
ASP A  24
 None
 0.67A 4a7tA-2owaA:
undetectable		 4a7tA-2owaA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		4 / 6 GLY A 125
ILE A 123
GLN A 127
VAL A 107
 None
 1.02A 4d39B-2owaA:
undetectable		 4d39B-2owaA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.66A 5qgjA-2owaA:
undetectable		 5qgjA-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.63A 5qglA-2owaA:
undetectable		 5qglA-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.64A 5qgnA-2owaA:
undetectable		 5qgnA-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.66A 5qguA-2owaA:
undetectable		 5qguA-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.68A 5qgvA-2owaA:
undetectable		 5qgvA-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.69A 5qgwA-2owaA:
undetectable		 5qgwA-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.68A 5qgxA-2owaA:
undetectable		 5qgxA-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.68A 5qh1A-2owaA:
undetectable		 5qh1A-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.67A 5qh4A-2owaA:
undetectable		 5qh4A-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.68A 5qh9A-2owaA:
undetectable		 5qh9A-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.67A 5qhcA-2owaA:
undetectable		 5qhcA-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.66A 5qheA-2owaA:
undetectable		 5qheA-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.69A 5qhfA-2owaA:
undetectable		 5qhfA-2owaA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 2owa ARFGAP-LIKE FINGER
DOMAIN CONTAINING
PROTEIN
(Cryptosporidium
parvum) 		3 / 3 VAL A  12
VAL A  18
GLN A  88
 None
 0.65A 5qhgA-2owaA:
undetectable		 5qhgA-2owaA:
21.61