SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ox5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6)	2ox5	SOXY PROTEIN (Paracoccus denitrificans)	5 / 9	THR Y 16 ALA Y 89 ALA Y 46 ALA Y 44 ALA Y 87	None	1.12A	5l5zK-2ox5Y: undetectable 5l5zL-2ox5Y: undetectable	5l5zK-2ox5Y: 20.87 5l5zL-2ox5Y: 17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6)	2ox5	SOXY PROTEIN (Paracoccus denitrificans)	5 / 9	THR Y 16 ALA Y 89 ALA Y 46 ALA Y 44 ALA Y 87	None	1.12A	5l5zY-2ox5Y: undetectable 5l5zZ-2ox5Y: undetectable	5l5zY-2ox5Y: 20.87 5l5zZ-2ox5Y: 17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X23_A_LSNA502_2 (CYTOCHROME P450 2C9)	2ox5	SOXY PROTEIN (Paracoccus denitrificans)	3 / 3	LEU Y 88 VAL Y 3 ASP Y 4	None	0.64A	5x23A-2ox5Y: undetectable	5x23A-2ox5Y: 14.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5L5Z_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6","2ox5","SOXY PROTEIN","Paracoccus denitrificans",5,"THR Y  16;ALA Y  89;ALA Y  46;ALA Y  44;ALA Y  87","None","1.12A","5l5zK-2ox5Y:undetectable;5l5zL-2ox5Y:undetectable","5l5zK-2ox5Y:20.87;5l5zL-2ox5Y:17.13"],["5L5Z_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5,PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6","2ox5","SOXY PROTEIN","Paracoccus denitrificans",5,"THR Y  16;ALA Y  89;ALA Y  46;ALA Y  44;ALA Y  87","None","1.12A","5l5zY-2ox5Y:undetectable;5l5zZ-2ox5Y:undetectable","5l5zY-2ox5Y:20.87;5l5zZ-2ox5Y:17.13"],["5X23_A_LSNA502_2","CYTOCHROME P450 2C9","2ox5","SOXY PROTEIN","Paracoccus denitrificans",3,"LEU Y  88;VAL Y   3;ASP Y   4","None","0.64A","5x23A-2ox5Y:undetectable","5x23A-2ox5Y:14.11"]]