SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oxl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 2oxl HYPOTHETICAL PROTEIN
YMGB
(Escherichia
coli) 		3 / 3 VAL A  72
ASP A  71
GLU A  30
 None
 0.65A 2qeuA-2oxlA:
3.1		 2qeuA-2oxlA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_C_ACTC141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 2oxl HYPOTHETICAL PROTEIN
YMGB
(Escherichia
coli) 		3 / 3 VAL A  72
ASP A  71
GLU A  30
 None
 0.64A 2qeuC-2oxlA:
2.9		 2qeuC-2oxlA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2oxl HYPOTHETICAL PROTEIN
YMGB
(Escherichia
coli) 		5 / 12 VAL A  33
GLY A  35
ALA A  37
LEU A  41
LEU A  43
 None
 0.98A 3hs6A-2oxlA:
undetectable		 3hs6A-2oxlA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 2oxl HYPOTHETICAL PROTEIN
YMGB
(Escherichia
coli) 		5 / 12 LEU A  34
ASN A  50
ILE A  53
ILE A  54
LEU A  57
 None
 0.58A 4nkvB-2oxlA:
undetectable		 4nkvB-2oxlA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2oxl HYPOTHETICAL PROTEIN
YMGB
(Escherichia
coli) 		3 / 3 ALA A  37
ASN A  40
LEU A  41
 None
 0.51A 5i1oA-2oxlA:
undetectable		 5i1oA-2oxlA:
24.59