SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oy3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 2oy3 MACROPHAGE RECEPTOR
MARCO
(Mus
musculus) 		3 / 3 PHE A 458
VAL A 515
TRP A 450
 None
 0.77A 2cc8A-2oy3A:
undetectable		 2cc8A-2oy3A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 2oy3 MACROPHAGE RECEPTOR
MARCO
(Mus
musculus) 		3 / 3 PHE A 458
VAL A 515
TRP A 450
 None
 0.76A 2ccbA-2oy3A:
undetectable		 2ccbA-2oy3A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_0
(CATECHOL
O-METHYLTRANSFERASE)		 2oy3 MACROPHAGE RECEPTOR
MARCO
(Mus
musculus) 		5 / 12 ASN A 486
VAL A 485
GLU A 491
GLY A 489
ARG A 466
 None
 1.29A 2cl5B-2oy3A:
undetectable		 2cl5B-2oy3A:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 2oy3 MACROPHAGE RECEPTOR
MARCO
(Mus
musculus) 		3 / 3 PHE A 458
VAL A 515
TRP A 450
 None
 0.76A 2vx9A-2oy3A:
undetectable		 2vx9A-2oy3A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 2oy3 MACROPHAGE RECEPTOR
MARCO
(Mus
musculus) 		5 / 12 GLU A 435
GLY A 476
ILE A 480
GLY A 474
ASN A 510
 None
 1.39A 3ps9A-2oy3A:
undetectable		 3ps9A-2oy3A:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2oy3 MACROPHAGE RECEPTOR
MARCO
(Mus
musculus) 		4 / 4 ASN A 452
SER A 471
ALA A 469
VAL A 515
 None
 1.40A 5nm5A-2oy3A:
undetectable		 5nm5A-2oy3A:
12.50