SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2oyo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		3 / 3 ALA A 115
VAL A  83
TRP A 118
 None
 0.94A 1c4dC-2oyoA:
undetectable
1c4dD-2oyoA:
undetectable		 1c4dC-2oyoA:
9.71
1c4dD-2oyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		3 / 3 TRP A 118
ALA A 115
VAL A  83
 None
 0.91A 1c4dC-2oyoA:
undetectable
1c4dD-2oyoA:
undetectable		 1c4dC-2oyoA:
9.71
1c4dD-2oyoA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		4 / 6 LEU A  30
TRP A  59
PHE A  45
VAL A  41
 None
 0.90A 1ibgH-2oyoA:
undetectable		 1ibgH-2oyoA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		4 / 7 PHE A 172
SER A 179
PHE A  62
GLY A  98
 None
 0.87A 2v0mC-2oyoA:
undetectable		 2v0mC-2oyoA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		4 / 6 GLU A 189
TYR A 190
PHE A  40
PRO A  42
 None
 1.47A 2vmyA-2oyoA:
undetectable		 2vmyA-2oyoA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		3 / 3 PHE A 172
CYH A  93
HIS A  97
 None
 1.20A 3u9fF-2oyoA:
undetectable		 3u9fF-2oyoA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		3 / 3 PHE A 172
CYH A  93
HIS A  97
 None
 1.26A 3u9fG-2oyoA:
undetectable		 3u9fG-2oyoA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		3 / 3 PHE A 172
CYH A  93
HIS A  97
 None
 1.30A 3u9fL-2oyoA:
undetectable		 3u9fL-2oyoA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		3 / 3 PHE A 172
CYH A  93
HIS A  97
 None
 1.21A 3u9fS-2oyoA:
undetectable		 3u9fS-2oyoA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		4 / 6 ILE A  38
TYR A  92
TYR A 190
PHE A  40
 None
 1.18A 4g10A-2oyoA:
undetectable		 4g10A-2oyoA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		4 / 6 PRO A  42
ILE A  12
TYR A 190
TYR A  92
 None
 1.22A 4g10A-2oyoA:
undetectable		 4g10A-2oyoA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 2oyo UNCHARACTERIZED
PEROXIDASE-RELATED
PROTEIN
(Deinococcus
geothermalis) 		5 / 12 GLU A 135
LEU A 105
ALA A 131
ARG A 102
ARG A 119
 None
 1.20A 5nd7B-2oyoA:
undetectable		 5nd7B-2oyoA:
19.19